Description

1-Piperazinecarboxylicacid,3-(Hydroxymethyl)-,Methylester,(S)-(9Ci) is a high-value, chiral piperazine derivative that serves as a critical building block in advanced organic synthesis. Its significance lies in its role as a versatile intermediate for constructing complex molecules with specific stereochemistry, which is essential for developing bioactive compounds. This product is primarily needed by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) agents and other therapeutic candidates.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel active pharmaceutical ingredients (APIs).
• CNS Drug Development: Used in the synthesis of potential therapeutic agents targeting the central nervous system.
• Asymmetric Synthesis: Employed as a building block to introduce the (S)-configured piperazine moiety in complex organic molecules.
• Medicinal Chemistry Research: Utilized in structure-activity relationship (SAR) studies and lead optimization for new drug candidates.
• Chemical Biology Probes: Serves as a precursor for creating specialized molecular probes used in biochemical research.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs performing bespoke synthesis for clients.

Basic Information

Product Name	1-Piperazinecarboxylicacid,3-(Hydroxymethyl)-,Methylester,(S)-(9Ci)
CAS No.	126766-61-8
Molecular Formula	C7H14N2O3
Molecular Weight	174.20 g/mol
Synonyms	(S)-3-(Hydroxymethyl)piperazine-1-carboxylic acid methyl ester; Methyl (S)-3-(hydroxymethyl)piperazine-1-carboxylate; (S)-Methyl 3-(hydroxymethyl)piperazine-1-carboxylate; (S)-1-(Methoxycarbonyl)-3-(hydroxymethyl)piperazine; (3S)-3-(Hydroxymethyl)-1-piperazinecarboxylic acid methyl ester; (S)-3-Hydroxymethyl-piperazine-1-carboxylic acid methyl ester; (S)-N-Boc-3-piperazinemethanol methyl ester derivative; CAS 126766-61-8
EINECS	Contact for details

Quality Control

Our production of this chiral intermediate adheres to strict quality control protocols to ensure batch-to-batch consistency and high chemical purity, which is paramount for sensitive pharmaceutical R&D. All material is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity (typically by HPLC), chiral purity, and impurity profiles. We support development work with specifications that can meet the needs of early-stage research through to pre-clinical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.