Description

2-Bromo-1-Pyrazin-2-Yl-Ethanone Hydrobromide is a high-purity, versatile brominated pyrazine derivative used as a key synthetic intermediate in advanced organic chemistry. This compound is valued for its reactivity, particularly in nucleophilic substitution and cross-coupling reactions, enabling the construction of complex heterocyclic scaffolds. It is primarily sought by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of potential drug candidates, especially in medicinal chemistry programs targeting kinase inhibitors and other biologically active molecules.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the pyrazine core for bioactivity.
• Chemical Synthesis: Serves as an electrophilic reagent for introducing the 2-pyrazinoyl moiety into more complex molecular architectures via alkylation or further functionalization.
• Material Science: Employed in the research and development of organic electronic materials and ligands for catalytic systems.
• Academic & Contract Research: Essential for methodological studies and novel route development in synthetic organic chemistry laboratories worldwide.

Basic Information

Product Name	2-Bromo-1-Pyrazin-2-Yl-Ethanone Hydrobromide
CAS No.	126353-32-0
Molecular Formula	C6H6Br2N2O
Molecular Weight	289.93 g/mol
Synonyms	2-Bromo-1-(pyrazin-2-yl)ethanone hydrobromide; 2-Bromo-1-(2-pyrazinyl)ethanone HBr; Ethanone, 2-bromo-1-(2-pyrazinyl)-, hydrobromide; 2-Pyrazinyl bromomethyl ketone hydrobromide; α-Bromo-2-pyrazinyl methyl ketone hydrobromide; Bromopyrazin-2-ylmethyl ketone hydrobromide
EINECS	Contact for details

Quality Control

Every batch of 2-Bromo-1-Pyrazin-2-Yl-Ethanone Hydrobromide is manufactured under strict quality management protocols. We provide comprehensive analytical data to ensure the material meets the high standards required for research and development. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles by HPLC, NMR, and other relevant techniques is supplied with each shipment to guarantee reproducible results and process reliability for our clients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.