Description

2-Piperazinecarboxylicacid,6-Oxo-,Methylester,(2R)-(9Ci) is a high-purity chiral piperazine derivative, a critical building block in advanced organic synthesis. Its precise stereochemistry and functional groups make it an invaluable intermediate for constructing complex molecules with high enantiomeric purity. This compound is primarily sought after by pharmaceutical R&D and fine chemical manufacturers for the development of active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated heterocyclic scaffolds.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and production of novel drug candidates, especially protease inhibitors and central nervous system (CNS) agents.
• Fine Chemical Synthesis: Used in the multi-step synthesis of complex organic molecules for agrochemicals and specialty materials.
• Bioconjugation & Peptidomimetics: Serves as a constrained scaffold for designing peptide analogs and bioconjugation linkers to improve metabolic stability.
• Catalyst & Ligand Development: Employed as a precursor for synthesizing chiral ligands and organocatalysts used in asymmetric synthesis.
• Academic & Industrial Research: A valuable reagent for methodological development in organic chemistry and medicinal chemistry programs.

Basic Information

Product Name	2-Piperazinecarboxylicacid,6-Oxo-,Methylester,(2R)-(9Ci)
CAS No.	126330-91-4
Molecular Formula	C7H12N2O3
Molecular Weight	172.18 g/mol
Synonyms	(2R)-6-Oxo-2-piperazinecarboxylic acid methyl ester; Methyl (2R)-6-oxopiperazine-2-carboxylate; (R)-Methyl 6-oxopiperazine-2-carboxylate; (R)-2-(Methoxycarbonyl)-1,4-diazinan-6-one; 2-Piperazinecarboxylic acid, 6-oxo-, methyl ester, (2R)-; (R)-6-Oxo-piperazine-2-carboxylic acid methyl ester; (2R)-Methyl 6-oxo-1,4-diazinane-2-carboxylate
EINECS	Contact for details

Quality Control

Our 2-Piperazinecarboxylicacid,6-Oxo-,Methylester,(2R)-(9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the stringent requirements for pharmaceutical R&D. A detailed Certificate of Analysis (COA) providing purity, enantiomeric excess, and impurity profile is supplied with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.