Description

2-(5,7-Dioxo-5,7-Dihydro-6H-Pyrrolo[3,4-B]Pyrazin-6-Yl)-4-Methylpentanoic Acid is a high-purity, non-natural amino acid derivative and a key heterocyclic building block. This compound matters as a sophisticated intermediate for the synthesis of complex molecules, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced material sectors for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Used in the development of new active ingredients for crop protection with potential novel modes of action.
• Chemical Biology & Proteomics: Serves as a specialty amino acid analog for peptide modification and probe development in target identification studies.
• Material Science: A precursor for functionalized polymers and organic electronic materials due to its conjugated pyrrolopyrazine core.
• Academic & Contract Research: Essential for synthetic chemistry research in universities and CROs (Contract Research Organizations) exploring new heterocyclic chemistry.
• Peptidomimetics Development: Incorporated into peptide backbones to enhance metabolic stability, bioavailability, and binding affinity.

Basic Information

Product Name	2-(5,7-Dioxo-5,7-Dihydro-6H-Pyrrolo[3,4-B]Pyrazin-6-Yl)-4-Methylpentanoic Acid
CAS No.	126310-30-3
Molecular Formula	C12H13N3O4
Molecular Weight	263.25 g/mol
Synonyms	4-Methyl-2-(5,7-dioxo-6H-pyrrolo[3,4-b]pyrazin-6-yl)pentanoic acid; 6-(1-Carboxy-3-methylbutyl)-5,7-dihydro-6H-pyrrolo[3,4-b]pyrazine-5,7-dione; 2-(5,7-Dioxo-5,7-dihydro-6H-pyrrolo[3,4-b]pyrazin-6-yl)-4-methylpentanoic acid; Leucine pyrrolopyrazinedione derivative; (S)-2-(5,7-Dioxo-5,7-dihydro-6H-pyrrolo[3,4-b]pyrazin-6-yl)-4-methylpentanoic acid (potential stereoisomer); Heterocyclic leucine derivative; Pyrrolo[3,4-b]pyrazine-5,7-dione, 6-(1-carboxy-3-methylbutyl)-5,7-dihydro-
EINECS	Contact for details

Quality Control

Our 2-(5,7-Dioxo-5,7-Dihydro-6H-Pyrrolo[3,4-B]Pyrazin-6-Yl)-4-Methylpentanoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and MS, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.