Description

2,5-Piperazinedione,3-Hydroxy-3,6-Dimethyl-,trans-(9Ci) is a specialized diketopiperazine derivative, a class of compounds known for their significant biological and chemical utility. This compound serves as a key chiral building block and intermediate in the synthesis of complex molecules, particularly in pharmaceutical research and development. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing novel active ingredients and exploring new synthetic pathways.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the research and synthesis of potential drug candidates, including protease inhibitors and other biologically active molecules.
• Agrochemical Research: Used in the development of novel pesticides and herbicides, leveraging its stereochemistry to create specific bioactive conformations.
• Peptidomimetics & Drug Design: Serves as a constrained scaffold in medicinal chemistry for designing peptide analogs with improved metabolic stability and bioavailability.
• Fine Chemical Synthesis: Employed as a building block for the production of complex, high-value specialty chemicals and catalysts.
• Academic & Industrial R&D: Utilized in research laboratories for studying reaction mechanisms, asymmetric synthesis, and the development of new synthetic methodologies.

Basic Information

Product Name	2,5-Piperazinedione,3-Hydroxy-3,6-Dimethyl-,trans-(9Ci)
CAS No.	126266-50-0
Molecular Formula	C6H10N2O3
Molecular Weight	158.16 g/mol
Synonyms	trans-3-Hydroxy-3,6-dimethylpiperazine-2,5-dione; (3R,6R)-3-Hydroxy-3,6-dimethylpiperazine-2,5-dione; (R,R)-3-Hydroxy-3,6-dimethyl-2,5-piperazinedione; 3-Hydroxy-3,6-dimethyl-2,5-diketopiperazine; Diketopiperazine derivative; Chiral hydroxy dimethyl diketopiperazine; (3R,6R)-HDP; trans-HDP
EINECS	Contact for details

Quality Control

Our 2,5-Piperazinedione,3-Hydroxy-3,6-Dimethyl-,trans-(9Ci) is produced under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and chiral purity analysis, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and chiral excess is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture uptake, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.