Description

5,8,11,14,17-Eicosapentaenoic Acid, Ethyl Ester, (5E,8Z,11Z,14Z,17Z)- is a high-purity ethyl ester derivative of the essential ω-3 fatty acid eicosapentaenoic acid (EPA). This form offers enhanced stability and bioavailability, making it a critical intermediate for advanced nutritional and pharmaceutical formulations. It is primarily utilized by manufacturers in the nutraceutical, pharmaceutical, and research sectors for the development of high-concentration ω-3 supplements, active pharmaceutical ingredients (APIs), and biochemical standards.

Application

• Pharmaceutical Intermediates: A key starting material for the synthesis of prescription-grade ω-3 medications and high-potency APIs targeting cardiovascular and inflammatory conditions.
• Nutraceutical Formulations: Used in the production of concentrated dietary supplements, softgel capsules, and functional foods requiring a stable and highly bioavailable source of EPA.
• Biomedical Research: Serves as a standard and reagent in lipidomics research, metabolic studies, and the investigation of inflammation and cell signaling pathways.
• Cosmeceuticals: Incorporated into advanced skincare products for its anti-inflammatory properties and benefits for skin health.
• Reference Standards: Employed as a certified reference material (CRM) in analytical laboratories for quality control and method validation of ω-3 products.

Basic Information

Product Name	5,8,11,14,17-Eicosapentaenoic Acid, Ethyl Ester, (5E,8Z,11Z,14Z,17Z)-
CAS No.	125827-50-1
Molecular Formula	C22H34O2
Molecular Weight	330.51 g/mol
Synonyms	EPA Ethyl Ester; Ethyl Eicosapentaenoate; Ethyl (5E,8Z,11Z,14Z,17Z)-5,8,11,14,17-Eicosapentaenoate; Ethyl (5E,8Z,11Z,14Z,17Z)-Icosapentaenoate; Ethyl All-cis-5,8,11,14,17-Eicosapentaenoate; ω-3 Ethyl Ester 90 (EPA); E-EPA; AMR101 (Vascepa® API Intermediate)
EINECS	Contact for details

Quality Control

Our 5,8,11,14,17-Eicosapentaenoic Acid, Ethyl Ester is manufactured under strict quality systems. Each batch is analyzed to ensure it meets stringent specifications for purity, oxidation parameters, and heavy metals, aligning with industry standards for pharmaceutical and nutraceutical ingredients. Comprehensive Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store unopened containers at -20°C or below under an inert atmosphere (e.g., nitrogen). Once opened, use promptly and minimize exposure to air, heat, and light. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Clear, pale yellow to yellow oil
Identification (IR)	Conforms
Assay (HPLC)	≥ 90.0% (Total EPA Ethyl Ester)
Peroxide Value (PV)	≤ 5.0 meq/kg
Anisidine Value (AV)	≤ 20.0
Total Oxidation (TOTOX)	≤ 26.0
Heavy Metals (as Pb)	≤ 10 ppm
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.