Description

m-Peg9-Bromide is a high-purity, monodisperse polyethylene glycol (PEG) derivative functionalized with a bromide end-group. This compound serves as a critical bifunctional linker and building block for the controlled synthesis of advanced materials and bioconjugates. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and specialty chemical sectors who require precise molecular architecture for drug delivery systems, diagnostic agents, and surface modification.

Application

• Pharmaceutical Linker: A key intermediate in the synthesis of antibody-drug conjugates (ADCs), peptide-drug conjugates, and other targeted therapeutics.
• PEGylation Reagent: Used to introduce a reactive bromoalkyl handle onto proteins, peptides, or small molecules to facilitate further conjugation or to impart stealth properties.
• Polymer Chemistry: Serves as a macro-initiator or chain transfer agent in controlled radical polymerization (e.g., ATRP) to create well-defined block copolymers.
• Surface Functionalization: Employed to modify nanoparticles, quantum dots, or solid supports with a PEG spacer and a reactive bromine terminus for subsequent immobilization of biomolecules.
• Cross-linking Agent: Utilized in the preparation of hydrogels, networks, and dendrimers where a defined PEG length is required.
• Diagnostic Probes: Acts as a spacer in the construction of imaging agents and biosensors to reduce non-specific binding and improve solubility.

Basic Information

Product Name	m-Peg9-Bromide
CAS No.	125562-30-3
Molecular Formula	C19H39BrO9
Molecular Weight	491.41 g/mol
Synonyms	2,5,8,11,14,17,20,23,26-Nonaoxaoctacosan-28-yl Bromide; 1-Bromo-3,6,9,12,15,18,21,24,27-nonaoxanonacosane; Bromo-PEG9-OH; 9-Amino-3,6-dioxaoctyl Bromide (common naming); mPEG9-Br; Monomethoxy PEG9 Bromide; α-Methoxy-ω-bromo-nonaethylene glycol; Poly(ethylene glycol) methyl ether brominated (n~9)
EINECS	Contact for details

Quality Control

Our m-Peg9-Bromide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR, HPLC, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and reactivity. Keep container tightly sealed in a desiccated environment when not in use.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Assay	≥ 90.0%
Water Content (KF)	≤ 1.0%
Molecular Weight (MS)	491.41 ± 5

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.