Description

5-Hydroxy-6-Mercapto-7,9,11,14-Eicosatetraenoic Acid is a specialized, high-purity eicosanoid derivative of significant interest in biochemical research and pharmaceutical development. This compound serves as a critical intermediate and reference standard for studying lipid mediator pathways, inflammation, and cellular signaling mechanisms. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and advanced life science sectors who require precise, reliable chemical tools for drug discovery and metabolic studies.

Application

• Biochemical Research: A key intermediate and reference standard for investigating eicosanoid biosynthesis, leukotriene pathways, and lipid-based cell signaling.
• Pharmaceutical R&D: Used in the discovery and development of novel anti-inflammatory agents, enzyme inhibitors, and receptor modulators targeting arachidonic acid metabolism.
• Metabolomics & Biomarker Studies: Serves as a critical analytical standard for the identification and quantification of oxylipins and related metabolites in complex biological samples.
• Enzyme Activity Assays: Employed as a substrate or inhibitor in assays for lipoxygenase (LOX) and other enzymes involved in the eicosanoid cascade.
• Academic Research: Utilized in university and institutional labs for fundamental studies on inflammation, oxidative stress, and immune response mechanisms.
• Contract Research Organizations (CROs): Supplied to CROs and analytical service providers for client-sponsored research and custom synthesis projects.

Basic Information

Product Name	5-Hydroxy-6-Mercapto-7,9,11,14-Eicosatetraenoic Acid
CAS No.	125467-37-0
Molecular Formula	C₂₀H₃₂O₃S
Molecular Weight	352.53 g/mol
Synonyms	5-Hydroxy-6-mercapto-7,9,11,14-eicosatetraenoic acid; 5-Hydroxy-6-sulfanyl-7,9,11,14-eicosatetraenoic acid; 6-Mercapto-5-hydroxy-7,9,11,14-eicosatetraenoic acid; 5-Hydroxy-6-thiol-7,9,11,14-eicosatetraenoic acid; 5(S)-Hydroxy-6(R)-mercapto-7,9-trans-11,14-cis-eicosatetraenoic acid; 5-HETE-6-thiol; Leukotriene analog
EINECS	Contact for details

Quality Control

Our 5-Hydroxy-6-Mercapto-7,9,11,14-Eicosatetraenoic Acid is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity, suitable for sensitive research applications. Each lot undergoes comprehensive analytical characterization, including HPLC, NMR, and MS, to verify identity and purity. Certificates of Analysis (COA) with detailed chromatographic data are provided to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the sealed container to reach room temperature before opening to minimize moisture condensation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.