Description

6-(1-Hydroxyethyl)-2-(5-Chloro-2-Oxobenzoxazolin-3-Yl)-1-Methyl-1-Carbapen-2-Em-3-Carboxylic Acid is a key advanced pharmaceutical intermediate in the carbapenem class of β-lactam antibiotics. This compound matters for its critical role in the synthesis of novel, potent antibacterial agents designed to combat resistant pathogens. It is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development and production of next-generation antibiotics, particularly those targeting gram-positive and gram-negative bacterial infections.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the multi-step synthesis of advanced carbapenem antibiotic active pharmaceutical ingredients (APIs).
• Antibacterial Drug Research: Used in medicinal chemistry and process R&D for developing new β-lactam antibiotics with improved efficacy and resistance profiles.
• Reference Standard: Employed as a high-purity analytical standard for quality control and method development in pharmaceutical laboratories.
• Process Chemistry: Utilized in scaling up and optimizing synthetic routes for the commercial manufacturing of carbapenem-based drugs.
• Academic Research: Applied in university and institutional studies focused on the structure-activity relationships (SAR) of β-lactam compounds.

Basic Information

Product Name	6-(1-Hydroxyethyl)-2-(5-Chloro-2-Oxobenzoxazolin-3-Yl)-1-Methyl-1-Carbapen-2-Em-3-Carboxylic Acid
CAS No.	125412-71-7
Molecular Formula	C17H15ClN2O6
Molecular Weight	378.76 g/mol
Synonyms	(5R,6S)-6-[(1R)-1-Hydroxyethyl]-2-[(5-Chloro-2-oxo-1,3-benzoxazol-3(2H)-yl)]-1-methyl-1-carbapen-2-em-3-carboxylic Acid; Carbapenem Intermediate 125412-71-7; 6-(1-Hydroxyethyl)-2-(5-chloro-2-oxobenzoxazolin-3-yl)-1-methylcarbapen-2-em-3-carboxylic Acid; 3-[(5R,6S)-3-Carboxy-6-[(1R)-1-hydroxyethyl]-1-methyl-2-carbapenem-2-yl]-5-chloro-1,3-benzoxazol-2(3H)-one
EINECS	Contact for details

Quality Control

Our 6-(1-Hydroxyethyl)-2-(5-Chloro-2-Oxobenzoxazolin-3-Yl)-1-Methyl-1-Carbapen-2-Em-3-Carboxylic Acid is manufactured under strict quality management systems. The product undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural identity suitable for pharmaceutical R&D and synthesis. Certificates of Analysis (COA) detailing purity, impurities, and other critical parameters are provided with each batch to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Single Maximum Unknown Impurity	≤ 1.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.