Description

1-(3-Hydroxybutan-2-Yl)-4-(4-(4-(4-Hydroxyphenyl)Piperazin-1-Yl)Phenyl)-1H-1,2,4-Triazol-5(4H)-One is a complex heterocyclic organic compound featuring a triazolone core linked to a hydroxyphenylpiperazine moiety. This molecular architecture makes it a valuable advanced pharmaceutical intermediate for research and development in medicinal chemistry. It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Key building block in the research and synthesis of new drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Used as a core scaffold or precursor for developing molecules with potential receptor-binding activity.
• Biochemical Research: Serves as a tool compound in studying enzyme inhibition or cellular signaling pathways.
• Fine Chemical Synthesis: Employed in multi-step organic synthesis for creating complex, high-value specialty chemicals.
• Contract Research & Manufacturing (CRAM): Supplied to organizations offering custom synthesis and process development services.

Basic Information

Product Name	1-(3-Hydroxybutan-2-Yl)-4-(4-(4-(4-Hydroxyphenyl)Piperazin-1-Yl)Phenyl)-1H-1,2,4-Triazol-5(4H)-One
CAS No.	125272-25-5
Molecular Formula	C22H26N6O3
Molecular Weight	422.48 g/mol
Synonyms	1-(3-Hydroxy-2-butyl)-4-[4-[4-(4-hydroxyphenyl)-1-piperazinyl]phenyl]-1,2,4-triazol-5(4H)-one; 4-[4-[4-(4-Hydroxyphenyl)piperazin-1-yl]phenyl]-1-(2-hydroxybutan-3-yl)-1,2,4-triazol-5-one; 1,2,4-Triazol-5(4H)-one, 1-(3-hydroxy-2-butyl)-4-[4-[4-(4-hydroxyphenyl)-1-piperazinyl]phenyl]-; CAS 125272-25-5
EINECS	Contact for details

Quality Control

Our production of this high-purity pharmaceutical intermediate adheres to stringent quality protocols. Every batch is characterized and tested to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing specifications such as assay (HPLC), related substances, and residual solvents is provided with each shipment. Our quality system supports development under cGMP guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic (moisture-sensitive); ensure the container is sealed under an inert atmosphere if specified for the grade.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.