Description

2-N,n-Dimethylamino-6-Iodopyrazine CAS NO 125060-66-4 is a high-purity, functionalized pyrazine derivative characterized by its dimethylamino and iodo substituents. This compound serves as a versatile and valuable advanced pharmaceutical intermediate and organic synthesis building block, enabling the construction of complex molecules. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and material science sectors for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in research and development for creating novel herbicides, fungicides, and insecticides with specific modes of action.
• Ligand and Catalyst Development: The dimethylamino and halogen groups make it a useful scaffold for designing novel ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Employed as a monomer or functionalizing agent in the development of organic electronic materials, such as conductive polymers or organic light-emitting diodes (OLEDs).
• Chemical Biology Probes: Utilized in medicinal chemistry for structure-activity relationship (SAR) studies and as a building block for bioconjugation or probe synthesis.
• Cross-Coupling Reactions: The iodine atom is an excellent handle for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira), allowing for further structural diversification.

Basic Information

Product Name	2-N,n-Dimethylamino-6-Iodopyrazine
CAS No.	125060-66-4
Molecular Formula	C6H8IN3
Molecular Weight	249.06 g/mol
Synonyms	6-Iodo-2-(dimethylamino)pyrazine; 2-(Dimethylamino)-6-iodopyrazine; 6-Iodo-N,N-dimethylpyrazin-2-amine; 2-Dimethylamino-6-iodopyrazine; N,N-Dimethyl-6-iodopyrazin-2-amine
EINECS	Contact for details

Quality Control

Our 2-N,n-Dimethylamino-6-Iodopyrazine is manufactured under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.