Description

4-Amino-5-(Pyrazin-2-Yl)-4H-1,2,4-Triazole-3-Thiol is a heterocyclic organic compound featuring a fused triazole-pyrazine core structure with a thiol functional group. This molecular architecture makes it a versatile and high-value building block for advanced chemical synthesis, particularly in the development of novel active ingredients. It is primarily sought after by pharmaceutical R&D and agrochemical sectors for its potential as a key intermediate in creating new therapeutic agents and crop protection products.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly those targeting infectious diseases, cancer, and central nervous system disorders.
• Agrochemical Research: Serves as a core scaffold for developing new generations of herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Ligand in Coordination Chemistry: Utilized in the preparation of metal-organic frameworks (MOFs) and catalysts due to its nitrogen and sulfur donor atoms.
• Material Science Research: Investigated as a monomer or additive for creating specialized polymers and functional materials with unique electronic or optical properties.
• Biochemical Probe Development: Used in medicinal chemistry to create molecular probes for studying enzyme mechanisms and biological pathways.

Basic Information

Product Name	4-Amino-5-(Pyrazin-2-Yl)-4H-1,2,4-Triazole-3-Thiol
CAS No.	124991-69-1
Molecular Formula	C6H5N7S
Molecular Weight	207.22 g/mol
Synonyms	4-Amino-5-(2-pyrazinyl)-4H-1,2,4-triazole-3-thiol; 4-Amino-5-pyrazin-2-yl-1,2,4-triazole-3-thiol; 5-(Pyrazin-2-yl)-4H-1,2,4-triazole-3-thiol-4-amine; 4-Amino-5-(2-pyrazinyl)-1,2,4-triazole-3-thiol; 3-Thiol-4-amino-5-(2-pyrazinyl)-1,2,4-triazole; 124991-69-1; 4-ATPT
EINECS	Contact for details

Quality Control

Our production of 4-Amino-5-(Pyrazin-2-Yl)-4H-1,2,4-Triazole-3-Thiol adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR, to ensure it meets exacting research and development standards. A detailed Certificate of Analysis (COA) is provided with each shipment, guaranteeing traceability and consistent batch-to-batch quality.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, long-term storage under an inert atmosphere (e.g., nitrogen or argon) is recommended for optimal stability. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.