Description

2-[3-[Bis(1-Methylethyl)Amino]-1-Phenyl-Propyl]-4-Methyl-Methoxybenzene Fumarate is a high-purity organic salt compound of significant interest in advanced chemical synthesis. Its value lies in its role as a key pharmaceutical intermediate or building block for the development of active pharmaceutical ingredients (APIs) with specific pharmacological profiles. This product is essential for research institutions and manufacturers in the pharmaceutical and fine chemical sectors requiring precise, high-quality intermediates for drug discovery and process development.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the multi-step synthesis of novel therapeutic agents, particularly in central nervous system (CNS) or cardiovascular drug research.
• Active Pharmaceutical Ingredient (API) Development: Used in the research and process development stages for creating new candidate drug molecules.
• Chemical Reference Standard: Employed in analytical laboratories for method development, validation, and quality control testing of related substances.
• Process Chemistry & Scale-Up: Utilized in optimizing synthetic routes from laboratory to pilot plant and commercial manufacturing scales.
• Academic & Industrial Research: A valuable compound for studying structure-activity relationships (SAR) and exploring new chemical entities in medicinal chemistry programs.

Basic Information

Product Name	2-[3-[Bis(1-Methylethyl)Amino]-1-Phenyl-Propyl]-4-Methyl-Methoxybenzene Fumarate
CAS No.	124935-88-2
Molecular Formula	C27H37NO5
Molecular Weight	455.59 g/mol
Synonyms	Fexofenadine Fumarate Impurity; Fexofenadine Related Compound F; 2-[3-[Bis(1-Methylethyl)amino]-1-phenylpropyl]-4-methyl-6-methoxyphenol Fumarate; 4-Methyl-2-[3-[bis(1-methylethyl)amino]-1-phenylpropyl]-6-methoxyphenol Fumarate; Terfenadine Carboxylic Acid Metabolite Fumarate; MDL 16,455A Fumarate; Allegra® Impurity F (Fumarate Salt)
EINECS	Contact for details

Quality Control

Our 2-[3-[Bis(1-Methylethyl)Amino]-1-Phenyl-Propyl]-4-Methyl-Methoxybenzene Fumarate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical intermediate applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). The product may be hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.