Description

Dynemicin is a potent enediyne antibiotic compound, identified by CAS NO 124759-75-7, known for its unique molecular architecture that enables DNA cleavage. This compound matters for its significant role as a biochemical tool in oncology research and as a lead structure for the development of novel anticancer agents. It is primarily needed by pharmaceutical R&D laboratories, academic research institutions, and biotechnology companies focused on DNA-targeting therapeutics and molecular biology.

Application

• Anticancer Research: Serves as a critical biochemical probe for studying DNA damage and repair mechanisms in oncology.
• Pharmaceutical Development: Acts as a lead compound for the design and synthesis of novel enediyne-based chemotherapeutic agents.
• Molecular Biology Studies: Used to investigate sequence-specific DNA cleavage and genomic interactions.
• Biochemical Mechanism Studies: Employed in research to understand the Bergman cyclization and its biological consequences.
• Antibiotic Research: Studied for its potent antimicrobial properties and mode of action against resistant strains.

Basic Information

Product Name	Dynemicin
CAS No.	124759-75-7
Molecular Formula	C30H28N2O8
Molecular Weight	544.56 g/mol
Synonyms	Dynemicin A; Antibiotic BMY 40538; BMY-40538; 9,10-Dehydro-12,13-didehydro-4,6,11-trihydroxy-10-methyl-8-[2-(methylamino)ethyl]-5,12-naphthacenedione; (1S,5R,6S,8R,9S,10S,12R,13S,14R)-14-Ethyl-4,6,11-trihydroxy-10-methyl-8-[2-(methylamino)ethyl]-5,12-dioxo-1,5,6,8,9,10,12,13,14,15-decahydro-1,13:9,15-dietheno-13a,15a-epimino-13aH-benzo[5,6]cycloocta[1,2,3-lm]naphtho[2,1,8-fga]acridine-9-carbonitrile
EINECS	Contact for details

Quality Control

Our Dynemicin is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research applications. Certificates of Analysis (COA) detailing purity, identity, and related substances are available upon request.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the container to reach room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	Yellow to orange solid
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.