Description

Phosphonoglycosphingolipid Fgl-Iib is a specialized, high-purity glycosphingolipid analog characterized by its unique phosphonate linkage. This compound is of significant interest in advanced biochemical research and development due to its role as a molecular probe and potential precursor in synthetic pathways. It is primarily utilized by researchers and developers in the pharmaceutical, biotechnology, and life science sectors for investigating cell signaling, membrane biology, and as a building block for novel therapeutic agents.

Application

• Biochemical Research: Used as a critical reference standard and probe for studying glycosphingolipid metabolism, cell membrane structure, and receptor-ligand interactions.
• Pharmaceutical R&D: Serves as a key intermediate or precursor in the synthesis of novel drug candidates targeting metabolic disorders, cancer, and infectious diseases.
• Diagnostic Development: Employed in the development of diagnostic assays and kits for detecting specific enzymes or biomarkers related to sphingolipidoses and other lipid storage diseases.
• Glycobiology Studies: Essential for investigating the biological functions of complex carbohydrates and their role in cellular communication and immune response.
• Enzyme Inhibition Studies: Acts as a substrate analog or inhibitor for enzymes involved in glycosphingolipid biosynthesis and degradation pathways.
• Standards and Calibration: Provides a high-purity standard for analytical methods such as Mass Spectrometry (MS) and High-Performance Liquid Chromatography (HPLC) in quality control and research laboratories.

Basic Information

Product Name	Phosphonoglycosphingolipid Fgl-Iib
CAS No.	124363-52-6
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Fgl-Iib; Phosphonoglycosphingolipid Fgl IIb; Glycosphingolipid Fgl-Iib phosphonate analog; FGL-IIb phosphonolipid; (2S,3R,4E)-2-Azido-3-O-[(R)-1-carboxy-2-[(2S,3R,4E)-1,3-dihydroxyoctadec-4-en-2-yl]amino]-2-oxoethyl]-4-octadecene-1,3-diol 1-Phosphonate; Sphingolipid analog Fgl-Iib
EINECS	Contact for details

Quality Control

Our Phosphonoglycosphingolipid Fgl-Iib is manufactured under controlled conditions to ensure the highest standards of purity and consistency. Each batch undergoes rigorous analytical testing, including HPLC for purity assessment and spectroscopic methods (NMR, MS) for structural confirmation. We are committed to providing products suitable for research and development use. A comprehensive Certificate of Analysis (COA) detailing batch-specific results is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere. This product is hygroscopic (moisture-sensitive). Allow the vial to warm to room temperature in a desiccator before opening to prevent condensation and hydrolysis.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 2.0%
Solvent Residue (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.