Description

[4-(2-Hydroxy-Ethyl)-Piperazin-1-Yl]-Acetic Acid is a versatile piperazine derivative and bifunctional organic building block. This compound is valued for its ability to introduce both a carboxylic acid and a hydroxylated piperazine moiety into molecular structures, facilitating the synthesis of complex molecules. It is primarily sought by researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for applications in drug discovery, ligand synthesis, and as a key intermediate for functional materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds targeting neurological and cardiovascular diseases.
• Ligand and Chelator Synthesis: Used to create complexing agents and chelators for metal ions in catalytic systems or diagnostic imaging agents.
• Agrochemical Research: Serves as a precursor in the development of novel herbicides, fungicides, and plant growth regulators.
• Polymer Modification: Employed to introduce functional piperazine groups into polymer chains, enhancing properties like solubility or bioactivity.
• Bioconjugation Linker: Useful in bioconjugation chemistry for attaching drugs, dyes, or other molecules to proteins or peptides.
• Organic Synthesis Reagent: Acts as a versatile reagent in multi-step organic synthesis for constructing nitrogen-containing heterocycles.

Basic Information

Product Name	[4-(2-Hydroxy-Ethyl)-Piperazin-1-Yl]-Acetic Acid
CAS No.	124335-65-5
Molecular Formula	C8H16N2O3
Molecular Weight	188.22 g/mol
Synonyms	2-[4-(2-Hydroxyethyl)piperazin-1-yl]acetic acid; N-(2-Hydroxyethyl)piperazine-N'-acetic acid; 1-Carboxymethyl-4-(2-hydroxyethyl)piperazine; HEAA; 4-(2-Hydroxyethyl)-1-piperazineacetic acid; 1-Piperazineacetic acid, 4-(2-hydroxyethyl)-; (4-(2-Hydroxyethyl)piperazin-1-yl)acetic acid
EINECS	Contact for details

Quality Control

Our [4-(2-Hydroxy-Ethyl)-Piperazin-1-Yl]-Acetic Acid is produced under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. For cGMP or other specific regulatory grade requirements, please contact our technical sales team.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent absorption of moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.