Description

Piperidine, 1-Acetyl-2,5-Dimethyl-, trans- (9Ci) is a high-purity, stereochemically defined piperidine derivative, serving as a versatile and critical chiral building block in advanced organic synthesis. Its value lies in providing a rigid, substituted piperidine scaffold essential for constructing complex molecules with specific three-dimensional configurations. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs), agrochemicals, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel therapeutic agents, particularly in central nervous system (CNS) and metabolic disorder drug candidates.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides where the specific stereochemistry influences biological activity and selectivity.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing chiral ligands and organocatalysts used in asymmetric synthesis.
• Chemical Research: Employed in academic and industrial R&D for methodological studies in heterocyclic and stereoselective chemistry.
• Fine Chemical Production: Integral to the multi-step synthesis of complex, high-value specialty chemicals and flavors & fragrances.

Basic Information

Product Name	Piperidine, 1-Acetyl-2,5-Dimethyl-, trans- (9Ci)
CAS No.	124211-78-5
Molecular Formula	C9H17NO
Molecular Weight	155.24 g/mol
Synonyms	trans-1-Acetyl-2,5-dimethylpiperidine; (2R,5R)-1-Acetyl-2,5-dimethylpiperidine; (2S,5S)-1-Acetyl-2,5-dimethylpiperidine; 2,5-Dimethyl-1-piperidinyl methyl ketone; 1-(2,5-Dimethyl-1-piperidinyl)ethanone; NSC 406173; A trans-substituted N-Acetylpiperidine derivative
EINECS	Contact for details

Quality Control

Our Piperidine, 1-Acetyl-2,5-Dimethyl-, trans- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by GC or HPLC, to ensure high chemical and stereochemical purity suitable for demanding synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Chiral Purity (Chiral GC/HPLC)	≥ 98.0% de (trans-isomer)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.