Description

(S)-Hexahydro-Pyrrolo[1,2-A]Pyrazin-4-One CAS NO 124072-84-0 is a high-purity, chiral bicyclic lactam compound that serves as a critical advanced pharmaceutical intermediate (API intermediate). Its value lies in its role as a sophisticated building block for constructing complex molecules with specific stereochemistry, which is essential for developing active pharmaceutical ingredients (APIs). This compound is primarily needed by research institutions and pharmaceutical manufacturers engaged in the synthesis of novel therapeutics, particularly in areas like central nervous system (CNS) agents and other specialized drug discovery programs.

Application

• Pharmaceutical Intermediate: A key chiral scaffold in the synthesis of complex drug candidates and active pharmaceutical ingredients (APIs).
• Drug Discovery & Medicinal Chemistry: Used as a versatile building block for constructing novel molecular libraries and lead optimization in R&D.
• Synthesis of Biologically Active Compounds: Integral for creating molecules with potential activity in neurological and psychiatric disorders.
• Asymmetric Synthesis: Employed in chiral synthesis due to its defined (S)-configuration, enabling the production of enantiomerically pure compounds.
• Process Chemistry Development: Serves as a starting material or intermediate in scaling up synthetic routes from laboratory to pilot and commercial scale.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and development services for the pharma and biotech industries.

Basic Information

Product Name	(S)-Hexahydro-Pyrrolo[1,2-A]Pyrazin-4-One
CAS No.	124072-84-0
Molecular Formula	C7H12N2O
Molecular Weight	140.18 g/mol
Synonyms	(S)-Octahydropyrrolo[1,2-a]pyrazin-4-one; (S)-1,2,3,3a,4,5,6,7-Octahydropyrrolo[1,2-a]pyrazin-4-one; (S)-Hexahydro-1H-pyrrolo[1,2-a]pyrazin-4(6H)-one; (S)-4-Oxo-hexahydro-pyrrolo[1,2-a]pyrazine; (S)-Pyrrolo[1,2-a]pyrazin-4-one, hexahydro-; (S)-Bicyclic Lactam Intermediate
EINECS	Contact for details

Quality Control

Our (S)-Hexahydro-Pyrrolo[1,2-A]Pyrazin-4-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure it meets the high standards required for pharmaceutical R&D and production. Certificates of Analysis (COA) with detailed chromatographic data (HPLC, GC) and spectroscopic identification (IR, NMR) are provided to guarantee consistent quality, identity, and purity.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). This product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.