Description

1,24-Dihydroxyvitamin D2 is a biologically active metabolite of ergocalciferol (Vitamin D2), representing a high-purity reference standard and key intermediate in pharmaceutical research. This compound is critical for studying the nuanced metabolic pathways and physiological roles of vitamin D beyond its classical functions. It is primarily utilized by research institutions and pharmaceutical developers focused on endocrinology, bone health, and novel therapeutic applications.

Application

• Pharmaceutical Reference Standard: Serves as a high-purity calibrant for analytical methods (HPLC, LC-MS) in drug development and quality control.
• Biochemical Research: Used in in vitro and in vivo studies to investigate non-classical actions of vitamin D metabolites, including cell differentiation and immune modulation.
• Metabolic Pathway Analysis: A key intermediate for tracing and understanding the complex activation and catabolism pathways of Vitamin D2.
• Active Pharmaceutical Ingredient (API) Intermediate: Employed in the synthesis of more advanced vitamin D analogs and potential therapeutic agents.
• Diagnostic Kit Development: Used as a critical component in the development and calibration of immunoassays for vitamin D status assessment.

Basic Information

Product Name	1,24-Dihydroxyvitamin D2
CAS No.	124043-51-2
Molecular Formula	C₂₈H₄₄O₃
Molecular Weight	428.65 g/mol
Synonyms	1,24-Dihydroxyergocalciferol; 1α,24-Dihydroxyvitamin D2; 1α,24-Dihydroxyergocalciferol; 1,24(OH)₂D₂; 1,24-Dihydroxyvitamin D₂; (1R,3S,5Z)-5-[(2E)-2-[(1R,3aS,7aR)-1-[(2R,5S)-5-ethyl-6-methylheptan-2-yl]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylidenecyclohexane-1,3-diol
EINECS	Contact for details

Quality Control

Our 1,24-Dihydroxyvitamin D2 is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the container to reach room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.