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1,2-Distearoyl-Sn-Glycero-3-Phosphatidyl-Rac-Glycerol, Na Salt CAS NO 124011-52-5


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CAS No.:124011-52-5

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

1,2-Distearoyl-Sn-Glycero-3-Phosphatidyl-Rac-Glycerol, Sodium Salt is a synthetic, saturated phospholipid, specifically a phosphatidylglycerol (PG) derivative. This high-purity lipid is critical for constructing stable, biomimetic membrane systems and advanced drug delivery vehicles. It is essential for researchers and manufacturers in pharmaceutical development, liposome formulation, and biophysical research requiring precise membrane composition and functionality.

Application

  • Liposome & Lipid Nanoparticle (LNP) Formulation: A key structural component for creating stable, anionic liposomal bilayers used in drug and vaccine delivery systems.
  • Biomimetic Membrane Models: Used in research to create synthetic membranes that mimic bacterial or mitochondrial membranes for studying protein-lipid interactions.
  • Pulmonary Surfactant Research: Serves as a synthetic analog in studies related to lung surfactant composition and function.
  • Drug Encapsulation: Enhances the loading efficiency and stability of encapsulated therapeutic agents, particularly for sustained-release applications.
  • Cell Culture & Transfection Reagents: A component in specialized lipid mixtures used for cell membrane studies and non-viral gene delivery.
  • Analytical Standards: Used as a high-purity reference standard in chromatographic analysis (HPLC, LC-MS) for lipidomics research.

Basic Information

Product Name 1,2-Distearoyl-Sn-Glycero-3-Phosphatidyl-Rac-Glycerol, Sodium Salt
CAS No. 124011-52-5
Molecular Formula C42H80NaO10P
Molecular Weight 799.04 g/mol
Synonyms DSPG-Na; 1,2-Distearoyl-sn-glycero-3-phospho-rac-(1-glycerol) sodium salt; 18:0 PG Sodium Salt; Phosphatidylglycerol (18:0/18:0) sodium salt; PG(18:0/18:0) Na Salt; DS-PG; 1,2-Di-O-stearoyl-sn-glycero-3-phospho-(1'-rac-glycerol) sodium salt; Sodium 1,2-distearoyl-sn-glycero-3-phosphorac-(1-glycerol)
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Quality Control

Our high-purity phospholipids are manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets exacting standards for research and cGMP-guided applications. Certificates of Analysis (COA) with full traceability are provided.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under desiccant. This product is hygroscopic (moisture-sensitive). Allow the sealed vial to warm to room temperature before opening to prevent condensation and moisture uptake.

Specification

Item Specification
Appearance White to off-white powder or solid
Identification (HPLC/MS) Conforms
Purity (HPLC) ≥ 98.0%
Loss on Drying ≤ 2.0%
Residual Solvents (GC) Meets ICH guidelines
Heavy Metals ≤ 20 ppm
Bacterial Endotoxins < 10 EU/mg (if applicable)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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