Description

(±)11(12)-Eet CAS NO 123931-40-8 is a specialized epoxide derivative of eicosatetraenoic acid, serving as a critical synthetic intermediate and biochemical research tool. This compound is valued for its role in the study and synthesis of eicosanoid analogs, which are pivotal in understanding inflammatory and cellular signaling pathways. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and advanced organic synthesis sectors for developing novel therapeutic agents and conducting metabolic studies.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of eicosanoid-based drug candidates targeting inflammation and immune response.
• Biochemical Research: Used as a substrate or standard in enzymatic studies, particularly those involving cytochrome P450 and epoxide hydrolase pathways.
• Metabolite Synthesis: Essential for the preparation of labeled or unlabeled metabolites for mass spectrometry and pharmacokinetic research.
• Lipid Mediator Analog Development: Serves as a precursor for creating analogs of epoxy-eicosatrienoic acids (EETs) to investigate cardiovascular and renal functions.
• Organic Synthesis: Employed in advanced synthetic chemistry for constructing complex polyfunctional molecules due to its reactive epoxide group.
• Reference Standard: Provides a high-purity standard for analytical method development and quality control in related compound manufacturing.

Basic Information

Product Name	(±)11(12)-Eet
CAS No.	123931-40-8
Molecular Formula	C20H32O3
Molecular Weight	320.47 g/mol
Synonyms	(±)11,12-Epoxy-5,8,14-eicosatrienoic Acid; (±)11(12)-Epoxy-5Z,8Z,14Z-eicosatrienoic Acid; 11(12)-EET Racemate; (±)11,12-EET; 11,12-Epoxy-5,8,14-eicosatrienoic Acid; 11(12)-Epoxyeicosatrienoic Acid; Arachidonic Acid 11,12-Epoxide; (±)-11,12-Epoxyeicosatrienoic Acid
EINECS	Contact for details

Quality Control

Our (±)11(12)-Eet is produced under strict quality management protocols to ensure high purity and batch-to-batch consistency, suitable for demanding research and synthesis applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards for fine chemicals and can provide material tailored to specific research or cGMP-grade requirements upon request.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at -20°C or below to minimize oxidation and ensure long-term stability. Allow the container to reach room temperature in a desiccator before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	Colorless to pale yellow oil
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Solvent Residue (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.