Description

4H-1,3-Dioxin-5-Carbonylchloride,2,2-Dimethyl-4-Oxo-(9Ci) is a specialized heterocyclic building block featuring a reactive acid chloride group, making it a valuable intermediate for advanced organic synthesis. Its core value lies in enabling the efficient construction of complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. This high-purity intermediate is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries who require reliable, high-quality building blocks for their synthetic routes.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those with heterocyclic cores, for therapeutic areas such as oncology and central nervous system (CNS) disorders.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging its reactive site for creating potent bioactive molecules.
• Fine Chemical Production: Serves as a versatile building block for synthesizing complex flavors, fragrances, and advanced materials requiring specific dioxin-based structures.
• Academic & Industrial R&D: Employed in research laboratories for methodological studies, catalyst development, and exploring new chemical spaces in organic chemistry.
• Peptide Mimetic & Conjugate Chemistry: The acid chloride functionality is ideal for forming amide bonds, useful in creating peptide analogs or conjugating molecules to carriers or probes.
• Polymer Chemistry: Can act as a monomer or cross-linking agent in the synthesis of specialty polymers with unique thermal or chemical properties.

Basic Information

Product Name	4H-1,3-Dioxin-5-Carbonylchloride,2,2-Dimethyl-4-Oxo-(9Ci)
CAS No.	123826-40-4
Molecular Formula	C7H9ClO4
Molecular Weight	192.60 g/mol
Synonyms	2,2-Dimethyl-4-oxo-4H-1,3-dioxin-5-carbonyl chloride; 5-(Chlorocarbonyl)-2,2-dimethyl-4H-1,3-dioxin-4-one; 2,2-Dimethyl-4-oxo-4H-1,3-dioxine-5-carbonyl chloride; 4H-1,3-Dioxine-5-carbonyl chloride, 2,2-dimethyl-4-oxo-; 2,2-Dimethyl-4-oxo-1,3-dioxin-5-carbonyl chloride; 5-Carboxy-2,2-dimethyl-4H-1,3-dioxin-4-one acid chloride
EINECS	Contact for details

Quality Control

Our 4H-1,3-Dioxin-5-Carbonylchloride,2,2-Dimethyl-4-Oxo-(9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment. We adhere to cGMP guidelines where applicable to support our customers in regulated development pipelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Maximum Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.