Description

Ethyl 4-Cyanopiperidine-4-Carboxylate is a versatile and high-purity piperidine derivative, serving as a critical building block in advanced organic synthesis. Its bifunctional structure, featuring both a nitrile and an ester group, makes it a valuable intermediate for constructing complex molecular architectures. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of piperidine-based drug candidates, including potential central nervous system (CNS) agents and receptor modulators.
• Agrochemical Synthesis: Used in the development of novel pesticides and herbicides, where the piperidine scaffold contributes to biological activity.
• Fine Chemical Production: Employed as a versatile building block for creating complex molecules in custom synthesis and process development.
• Chemical Research: A valuable reagent in academic and industrial R&D for exploring new synthetic methodologies and heterocyclic chemistry.
• Ligand and Catalyst Development: The nitrile and ester functionalities can be modified to create novel ligands for metal complexes and catalysts.

Basic Information

Product Name	Ethyl 4-Cyanopiperidine-4-Carboxylate
CAS No.	123755-34-0
Molecular Formula	C9H14N2O2
Molecular Weight	182.22 g/mol
Synonyms	4-Cyano-4-(ethoxycarbonyl)piperidine; Ethyl 4-cyano-4-piperidinecarboxylate; 4-Carbethoxy-4-cyanopiperidine; 1,4-Piperidinedicarboxylic acid, 4-cyano-, 1-ethyl ester; 4-Cyano-piperidine-4-carboxylic acid ethyl ester; Piperidine-4-carboxylic acid, 4-cyano-, ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 4-Cyanopiperidine-4-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specifications and test results. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.