Description

2-(Ethylthio)Nicotinoyl Chloride is a specialized organic intermediate featuring a reactive acid chloride group and a thioether-substituted pyridine ring. This compound matters for its role as a critical building block in the synthesis of complex molecules, enabling the formation of amide bonds under mild conditions. It is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for creating novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of nicotinamide derivatives and other active pharmaceutical ingredients (APIs) with potential biological activity.
• Agrochemical Synthesis: Used in the development of novel pesticides, herbicides, and fungicides, leveraging its heterocyclic structure.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the synthesis of functionalized polymers and advanced organic materials with specific electronic properties.
• Custom Chemical Synthesis: Utilized by contract research and manufacturing organizations (CROs/CMOs) for bespoke synthesis projects and scale-up development.

Basic Information

Product Name	2-(Ethylthio)Nicotinoyl Chloride
CAS No.	123116-01-8
Molecular Formula	C8H8ClNOS
Molecular Weight	201.67 g/mol
Synonyms	2-(Ethylthio)nicotinoyl chloride; Nicotinoyl chloride, 2-(ethylthio)-; 2-(Ethylsulfanyl)nicotinoyl chloride; 3-Pyridinecarbonyl chloride, 2-(ethylthio)-; 2-(Ethylmercapto)nicotinoyl chloride
EINECS	Contact for details

Quality Control

Our 2-(Ethylthio)Nicotinoyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.