Description

1-Benzenesulfonyl-Piperidine-4-Carboxylic Acid is a high-purity, versatile sulfonamide derivative that serves as a critical building block in advanced organic synthesis. This compound is valued for its unique molecular scaffold, which combines a piperidine carboxylic acid moiety with a benzenesulfonyl group, enabling precise chemical modifications. It is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly those targeting neurological disorders, inflammation, and metabolic diseases.
• Agrochemical Research: Used in developing novel herbicides, fungicides, and insecticides by providing a functionalized heterocyclic core structure.
• Chemical Biology & Proteomics: Acts as a versatile scaffold or linker in the design of chemical probes, enzyme inhibitors, and activity-based protein profiling (ABPP) reagents.
• Material Science: Employed in the research and development of specialty polymers, ligands for catalysis, and advanced organic materials.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds and libraries for high-throughput screening.

Basic Information

Product Name	1-Benzenesulfonyl-Piperidine-4-Carboxylic Acid
CAS No.	122891-92-3
Molecular Formula	C13H15NO4S
Molecular Weight	281.33 g/mol
Synonyms	4-(Phenylsulfonyl)piperidine-1-carboxylic Acid; 1-(Phenylsulfonyl)piperidine-4-carboxylic Acid; Piperidine-4-carboxylic acid, 1-(benzenesulfonyl)-; 4-Carboxy-1-(phenylsulfonyl)piperidine; Benzenesulfonyl isonipecotic Acid; 1-Benzenesulfonyl-4-piperidinecarboxylic Acid; N-Benzenesulfonylisonipecotic Acid
EINECS	Contact for details

Quality Control

Our 1-Benzenesulfonyl-Piperidine-4-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and relevant industry standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.