Description

Phoslactomycin B is a potent and structurally unique natural product belonging to the phosphoglycolipid class of antibiotics. This compound matters for its significant biological activity, particularly as a selective inhibitor of eukaryotic protein phosphatases, making it a valuable tool in biochemical and pharmacological research. It is primarily needed by researchers in the fields of oncology, immunology, and cell signaling for investigating disease mechanisms and developing novel therapeutic strategies.

Application

• Biochemical Research: Used as a selective inhibitor of protein phosphatase 2A (PP2A) and other serine/threonine phosphatases in signal transduction studies.
• Oncology Research: Investigated for its antiproliferative and apoptosis-inducing effects in various cancer cell lines.
• Immunology Studies: Employed to study T-cell activation and cytokine production pathways.
• Antifungal Agent: Exhibits potent activity against a range of fungal pathogens, relevant for antifungal development research.
• Chemical Biology: Serves as a molecular probe to elucidate phosphatase-dependent cellular processes.
• Pharmaceutical Reference Standard: Used as a high-purity analytical standard for quality control and method development.

Basic Information

Item	Detail
Product Name	Phoslactomycin B
CAS No.	122856-26-2
Molecular Formula	C29H45NO9P
Molecular Weight	582.65 g/mol
Synonyms	Phoslactomycin B; FR-901512; L-681,512; Phosphazomycin B; Antibiotic FR-901512; (2E,4E,6E,8E)-9-[(2R,3S,4S,5S,6R)-4,5-Dihydroxy-6-[[(2S,3S)-3-hydroxy-2-[(1E,3E,5E,7E)-8-[(2R,3S,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]octa-1,3,5,7-tetraen-1-yl]pent-4-ynoyl]amino]-3-phosphonooxyoxan-2-yl]non-2,4,6,8-tetraenoic acid
EINECS	Contact for details

Quality Control

Our Phoslactomycin B is produced under stringent conditions to ensure the highest standards of purity and consistency, suitable for sensitive research applications. Each batch undergoes comprehensive analytical testing, including HPLC for purity and spectroscopic methods for structural confirmation. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance with your research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry, moisture-free environment. For long-term storage, consider storing under an inert atmosphere. Allow the product to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.