Description

2,5-Piperazinedione,1-Hydroxy-3-Methyl-,(S)-(9Ci) is a chiral, hydroxylated piperazinedione derivative, a specialized heterocyclic building block of significant interest in advanced organic synthesis. Its value lies in its unique stereochemistry and functional groups, which make it a critical precursor for constructing complex molecular architectures, particularly in the development of novel pharmaceuticals and bioactive compounds. This high-purity intermediate is essential for research and development chemists in the pharmaceutical, agrochemical, and fine chemical industries seeking to create enantiomerically pure target molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and synthesis of potential active pharmaceutical ingredients (APIs), especially for neurological and anti-infective agents.
• Peptidomimetic Research: Serves as a constrained scaffold or building block for designing and synthesizing peptidomimetics and protease inhibitors.
• Asymmetric Synthesis: Utilized as a starting material or auxiliary in asymmetric catalytic reactions to induce chirality in final products.
• Agrochemical Development: Employed in the discovery and synthesis of novel, enantiomerically pure herbicides or pesticides.
• Ligand and Catalyst Design: Used to develop novel chiral ligands for metal-catalyzed reactions or organocatalysts.
• Academic and R&D Laboratories: A valuable compound for methodological studies in organic chemistry and medicinal chemistry research programs.

Basic Information

Product Name	2,5-Piperazinedione,1-Hydroxy-3-Methyl-,(S)-(9Ci)
CAS No.	122556-76-7
Molecular Formula	C5H8N2O3
Molecular Weight	144.13 g/mol
Synonyms	(S)-1-Hydroxy-3-methylpiperazine-2,5-dione; (3S)-1-Hydroxy-3-methyl-2,5-piperazinedione; L-1-Hydroxy-3-methyl-2,5-diketopiperazine; (S)-1-Hydroxy-3-methyl-2,5-diketopiperazine; 1-Hydroxy-3-methyl-(S)-2,5-diketopiperazine; (S)-HMPD; Hydroxymethyl Diketopiperazine (S-enantiomer)
EINECS	Contact for details

Quality Control

Our 2,5-Piperazinedione,1-Hydroxy-3-Methyl-,(S)-(9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and synthesis. A detailed Certificate of Analysis (COA) providing batch-specific data for identity, purity, and chiral excess is supplied with every order.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound may be hygroscopic (moisture-sensitive); therefore, the container should be kept tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.