Description

2-Hydroxymethyl-Piperazine-2Hcl is a high-purity, versatile chemical building block and intermediate of significant commercial importance. Its functionalized piperazine core makes it a valuable precursor in the synthesis of complex molecules, particularly in the pharmaceutical and agrochemical sectors. This compound is essential for researchers and manufacturers developing active pharmaceutical ingredients (APIs), fine chemicals, and specialty materials requiring a functionalized heterocyclic scaffold.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of various drug candidates, including potential antivirals, antibiotics, and central nervous system (CNS) agents.
• Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and fungicides where the piperazine moiety imparts specific biological activity.
• Fine Chemical Production: Serves as a versatile intermediate in the manufacture of complex organic compounds for research and industrial applications.
• Ligand and Catalyst Preparation: Utilized in the development of chiral ligands and metal-organic catalysts for asymmetric synthesis.
• Polymer Modification: Acts as a functional monomer or cross-linking agent in the synthesis of specialty polymers and resins.
• Bioconjugation Chemistry: The hydroxymethyl group provides a handle for linking molecules to proteins, peptides, or other biomolecules.

Basic Information

Product Name	2-Hydroxymethyl-Piperazine-2Hcl
CAS No.	122323-87-9
Molecular Formula	C5H14N2O·2HCl
Molecular Weight	215.10 g/mol
Synonyms	2-(Hydroxymethyl)piperazine dihydrochloride; 1-Piperazineethanol, dihydrochloride; 2-Piperazin-1-ylethanol dihydrochloride; (2-Hydroxyethyl)piperazine dihydrochloride; HMP·2HCl; 2-Hydroxyethylpiperazine Dihydrochloride; Piperazine-1-ethanol dihydrochloride; N-(2-Hydroxyethyl)piperazine dihydrochloride
EINECS	Contact for details

Quality Control

Our 2-Hydroxymethyl-Piperazine-2Hcl is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including HPLC/GC purity, identity confirmation (IR, NMR), and tests for specific impurities. A Certificate of Analysis (COA) is supplied with each batch, detailing all specifications and test results. Our quality commitment supports applications requiring GMP-grade or high-purity research materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect product stability and handling properties. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.