Description

5-[4-[2-[n-Methyl-n-(2-Pyridinyl)Amino]Ethoxy]Benzylidene]-2,4-Thiazolidinedione is a high-purity pharmaceutical intermediate and research chemical with significant biological activity. This compound is valued for its role as a key synthetic precursor in the development of novel therapeutic agents. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and fine chemical manufacturers engaged in metabolic disorder research and drug discovery programs.

Application

• Pharmaceutical Intermediate: Critical building block in the synthesis of thiazolidinedione-based drug candidates targeting metabolic pathways.
• Research & Development: Used as a reference standard and active compound in biochemical and pharmacological studies, particularly for investigating insulin sensitization.
• Academic Research: Serves as a tool compound in university and institutional labs for studying PPAR-gamma (Peroxisome Proliferator-Activated Receptor gamma) agonists and related mechanisms.
• Fine Chemical Synthesis: Employed in custom synthesis and contract manufacturing for producing specialized, high-value chemical entities.
• Preclinical Studies: Utilized in the development and screening phases for new chemical entities (NCEs) aimed at treating type 2 diabetes and related disorders.

Basic Information

Product Name	5-[4-[2-[n-Methyl-n-(2-Pyridinyl)Amino]Ethoxy]Benzylidene]-2,4-Thiazolidinedione
CAS No.	122320-74-5
Molecular Formula	C19H19N3O3S
Molecular Weight	369.44 g/mol
Synonyms	5-[[4-[2-(N-Methyl-N-(2-pyridyl)amino)ethoxy]phenyl]methylene]thiazolidine-2,4-dione; 5-[4-[2-(N-Methyl-N-pyridin-2-ylamino)ethoxy]benzylidene]thiazolidine-2,4-dione; AD-5075; T-174; Thiazolidinedione derivative; PPAR-gamma ligand precursor; Insulin sensitizer intermediate
EINECS	Contact for details

Quality Control

Our 5-[4-[2-[n-Methyl-n-(2-Pyridinyl)Amino]Ethoxy]Benzylidene]-2,4-Thiazolidinedione is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The compound may be light-sensitive and should be handled under appropriate conditions to maintain stability. For long-term storage, consider storing under an inert atmosphere to prevent potential degradation.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.