Description

2,5-Piperazinedione,3-Methoxy-6-(1-Methylethyl)-,(3R-Trans)-(9Ci) is a high-purity, stereochemically defined piperazinedione derivative, a crucial chiral building block in advanced organic synthesis. Its specific stereochemistry and functional groups make it an invaluable intermediate for constructing complex molecular architectures with high enantiomeric purity. This compound is primarily sought by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), peptidomimetics, and other fine chemicals where precise stereocontrol is paramount.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of novel therapeutic agents, particularly for central nervous system (CNS) and anti-infective drugs.
• Peptidomimetics Research: Used as a constrained scaffold or building block to mimic peptide structures, aiding in the creation of more stable and bioavailable drug candidates.
• Asymmetric Synthesis: Employed as a starting material or intermediate in catalytic asymmetric reactions to introduce chiral complexity into target molecules.
• Chemical Biology Probes: Utilized in the synthesis of specialized probes for studying enzyme mechanisms and protein-ligand interactions.
• Agrochemical Research: Acts as a precursor in the development of new, stereospecific pesticides and herbicides.
• Academic & Process Chemistry: Used in methodological studies and scale-up process development for complex organic molecules.

Basic Information

Item	Details
Product Name	2,5-Piperazinedione,3-Methoxy-6-(1-Methylethyl)-,(3R-Trans)-(9Ci)
CAS No.	122092-89-1
Molecular Formula	C8H14N2O3
Molecular Weight	186.21 g/mol
Synonyms	(3R,6S)-3-Methoxy-6-isopropylpiperazine-2,5-dione; (3R-trans)-3-Methoxy-6-(1-methylethyl)-2,5-piperazinedione; 3-Methoxy-6-isopropyl-2,5-diketopiperazine; 3-Methoxy-6-isopropylpiperazine-2,5-dione; (3R,6S)-3-Methoxy-6-(propan-2-yl)piperazine-2,5-dione; 3-Methoxy-6-(1-methylethyl)-2,5-piperazinedione, (3R,6S)-; 2,5-Diketopiperazine derivative
EINECS	Contact for details

Quality Control

Every batch of 2,5-Piperazinedione,3-Methoxy-6-(1-Methylethyl)-,(3R-Trans)-(9Ci) is manufactured under strict quality management systems. We provide comprehensive analytical documentation, including HPLC/GC purity, chiral purity (enantiomeric excess), and identity confirmation (IR, NMR). A Certificate of Analysis (COA) detailing all specifications is available for each lot to ensure traceability and compliance with your research or cGMP starting material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% e.e.
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.