Description

11,12-Dihydroxyeicosatetraenoic Acid is a specialized eicosanoid metabolite derived from arachidonic acid. This compound is of significant interest in biochemical research for its role as a bioactive lipid mediator in various physiological and pathological processes. It is primarily utilized by researchers and developers in the pharmaceutical and life sciences sectors. The product is supplied under high-purity conditions to ensure reliable and reproducible experimental results.

Application

• Biochemical Research Standard: Used as a high-purity reference standard in analytical methods like LC-MS and HPLC for the quantification of eicosanoid pathways.
• Cell Signaling Studies: Investigated for its role in cellular signaling cascades, inflammation, and vascular biology to understand disease mechanisms.
• Drug Discovery & Development: Serves as a key metabolite or target molecule in screening assays for developing novel anti-inflammatory or cardiovascular therapeutics.
• Metabolomics & Lipidomics: An essential component in profiling studies to map lipid mediator networks and their changes in response to stimuli.
• Enzyme Activity Assays: Used as a substrate or product in assays to study the activity of cytochrome P450 epoxygenases and other related enzymes.

Basic Information

Product Name	11,12-Dihydroxyeicosatetraenoic Acid
CAS No.	122087-32-5
Molecular Formula	C₂₀H₃₂O₄
Molecular Weight	336.47 g/mol
Synonyms	11,12-DHET; 11,12-Dihydroxy-5Z,8Z,14Z-eicosatrienoic Acid; (±)11,12-DHET; 11,12-Dihydroxyeicosatrienoic Acid; 11(12)-DHET; 11,12-Dihydroxy-5,8,14-eicosatrienoic Acid; 11,12-Epoxy-5,8,14-eicosatrienoic Acid Diol; Arachidonic Acid 11,12-Diol
EINECS	Contact for details

Quality Control

Our 11,12-Dihydroxyeicosatetraenoic Acid is produced and handled under strict quality protocols to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to ISO 9001 quality management principles, and our analytical methods are validated to meet the rigorous standards required in pharmaceutical and analytical research.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the product to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	Colorless to pale yellow oil or solid
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95% (Area %)
Water Content (KF)	≤ 1.0 %
Solubility	Soluble in ethanol, DMSO, acetonitrile

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.