Description

L-A-Phosphatidylcholine, B-Docosa-*Hexaenoyl-γ-P is a highly specialized phospholipid characterized by a docosahexaenoyl (DHA) fatty acid chain esterified at the sn-2 position. This molecular structure is critical for its superior bioavailability and role in cellular membrane fluidity and signaling. It is an essential ingredient for advanced research and formulation in the pharmaceutical and nutraceutical sectors, where high-purity, structurally defined lipids are required. The compound with CAS number 122002-43-1 is sought after for its targeted biological activity and is a key component in developing next-generation lipid-based delivery systems and cognitive health supplements.

Application

• Pharmaceutical Excipient & Drug Delivery: As a critical component in liposomes, lipid nanoparticles (LNPs), and other advanced drug delivery systems for enhancing solubility and targeted release of active pharmaceutical ingredients (APIs).
• Nutraceutical & Dietary Supplements: A premium source of DHA-bound phosphatidylcholine for high-end cognitive support, eye health, and infant nutrition formulas, offering improved absorption over standard fish or algal oils.
• Biomedical & Life Science Research: Used in cell culture media supplements, membrane biophysics studies, and as a standard for analytical method development in lipidomics.
• Cosmeceuticals: Incorporated into anti-aging and skin barrier repair formulations for its membrane-stabilizing and nourishing properties.
• Functional Food Fortification: For the enrichment of foods and beverages with a highly bioavailable form of ω-3 phospholipids.

Basic Information

Product Name	L-A-Phosphatidylcholine, B-Docosa-*Hexaenoyl-γ-P
CAS No.	122002-43-1
Molecular Formula	C44H78NO8P
Molecular Weight	780.06 g/mol
Synonyms	1-Docosahexaenoyl-2-hydroxy-sn-glycero-3-phosphocholine; DHA-PC; 1-DHA-2-lyso-PC; PC(22:6/0:0); 1-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-2-hydroxy-sn-glycero-3-phosphocholine; Lyso-DHA-PC; γ-Linolenoyl Phosphatidylcholine (DHA variant); Phosphatidylcholine (16:0/22:6) (related common name)
EINECS	Contact for details

Quality Control

Our L-A-Phosphatidylcholine, B-Docosa-*Hexaenoyl-γ-P is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and isomer confirmation, to ensure it meets stringent specifications for research and GMP-grade applications. Certificates of Analysis (COA) detailing identity, assay, and impurity profiles are provided with every shipment. We support compliance with REACH, FDA, and other relevant regulatory frameworks for global supply.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation and hydrolysis. Under these conditions, the product is typically stable for at least 24 months. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white waxy solid or oily liquid
Identification (IR / NMR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Purity (Total Phospholipids)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Peroxide Value	≤ 5.0 meq/kg
Heavy Metals (as Pb)	≤ 10 ppm
Residual Solvents (GC)	Meets ICH guidelines
Microbial Limits	Meets Ph. Eur. / USP criteria

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.