Description

C20 Sphingomyelin (D18:1/20:0) is a high-purity, defined-chain sphingolipid essential for advanced biomedical research and formulation development. This compound serves as a critical building block for constructing and studying complex lipid membranes, directly impacting the study of cellular signaling, membrane biophysics, and lipid metabolism. It is primarily utilized by researchers and product developers in the pharmaceutical, biotechnology, and advanced cosmetics industries for applications ranging from drug delivery systems to high-end skincare formulations.

Application

• Biomedical Research: As a key component in model membrane systems (e.g., liposomes, lipid bilayers) for studying cell membrane structure, protein-lipid interactions, and lipid raft dynamics.
• Drug Delivery Development: Used in the formulation of advanced lipid nanoparticles (LNPs) and liposomal carriers to enhance the stability, targeting, and cellular uptake of therapeutic agents.
• Diagnostic Reagents: Incorporated into assay kits and diagnostic tools as a standard or substrate for enzymes like sphingomyelinase, relevant in metabolic disorder research.
• Cosmetic & Dermocosmetic Formulations: Employed in high-performance skincare products for its role in skin barrier function and ceramide precursor activity.
• Biochemical Standards: Serves as a certified reference material for quantitative analysis in lipidomics and metabolomics studies.
• Cell Culture & Media Supplements: Used to supplement serum-free media or create defined culture conditions for specialized cell lines.

Basic Information

Product Name	C20 Sphingomyelin (D18:1/20:0)
CAS No.	121999-68-6
Molecular Formula	C43H87N2O6P
Molecular Weight	759.14 g/mol
Synonyms	N-(20:0)-Sphingosylphosphorylcholine; N-Arachidoyl-D-erythro-sphingosylphosphorylcholine; SM(d18:1/20:0); N-Arachidoylsphingosylphosphorylcholine; Sphingomyelin (N-Arachidoyl-D-erythro-sphingosine); (2S,3R,4E)-2-Arachidoylamino-4-octadecene-1,3-diol 1-Phosphocholine; D-erythro-Sphingosine, N-arachidoyl-, 1-phosphocholine; LIPOID SM 20:0
EINECS	Contact for details

Quality Control

Our C20 Sphingomyelin is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (typically ≥98%), to ensure consistency and compliance with research-grade standards. Certificates of Analysis (COA) detailing batch-specific results are available upon request, providing full traceability and supporting your regulatory and documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). For long-term storage under inert atmosphere, seal under argon or nitrogen after opening. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (HPLC/MS)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 2.0 %
Heavy Metals	≤ 20 ppm
Solubility	Soluble in chloroform, methanol, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.