Description

12,13-Dihydroxyeicosa-5,8,10,14,17-Pentaenoic Acid is a specialized polyunsaturated fatty acid derivative, recognized for its role as a bioactive lipid mediator in various biochemical pathways. This compound is of significant interest for research and development in the life sciences, particularly in the study of inflammation, cell signaling, and metabolic processes. It is primarily utilized by pharmaceutical researchers, biochemical suppliers, and advanced academic laboratories focused on lipidomics and drug discovery.

Application

• Biochemical Research: Used as a reference standard or analytical standard in lipidomics and metabolomics studies to identify and quantify related eicosanoids.
• Pharmaceutical R&D: Serves as a key intermediate or tool compound in the investigation of novel anti-inflammatory and pro-resolving drug candidates.
• Cell Signaling Studies: Employed in vitro to study the mechanisms of action of dihydroxy fatty acids and their receptors in cellular models.
• Enzymology: Acts as a substrate for studying the activity and specificity of lipoxygenase and cytochrome P450 enzymes involved in eicosanoid biosynthesis.
• Nutritional Science: Investigated for its potential biological effects and metabolic fate as a derivative of dietary polyunsaturated fatty acids.

Basic Information

Product Name	12,13-Dihydroxyeicosa-5,8,10,14,17-Pentaenoic Acid
CAS No.	121979-38-2
Molecular Formula	C₂₀H₃₂O₄
Molecular Weight	336.47 g/mol
Synonyms	12,13-DiHETE; 12,13-Dihydroxy-5,8,10,14,17-eicosapentaenoic acid; (5Z,8Z,10E,12R,13S,14Z,17Z)-12,13-Dihydroxyeicosa-5,8,10,14,17-pentaenoic acid; 12(R),13(S)-DiHETE; 12,13-Dihydroxyeicosapentaenoic acid; 12,13-DiHETrE (historical); 12,13-Dihydroxy-EPA
EINECS	Contact for details

Quality Control

Our 12,13-Dihydroxyeicosa-5,8,10,14,17-Pentaenoic Acid is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the product to reach room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	Colorless to pale yellow oil or solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Water Content	≤ 0.5%
Solubility	Soluble in ethanol, DMSO; slightly soluble in aqueous buffer

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.