Description

Piroxicambeta-Cyclodextrin is an inclusion complex formed between the non-steroidal anti-inflammatory drug (NSAID) Piroxicam and β-Cyclodextrin. This complexation is engineered to enhance the solubility, dissolution rate, and bioavailability of the poorly water-soluble Piroxicam, addressing a key formulation challenge. It is primarily needed by pharmaceutical R&D and manufacturing companies focused on developing advanced oral and topical analgesic and anti-inflammatory products with improved performance profiles.

Application

• Pharmaceutical Formulations: Core ingredient in advanced solid dosage forms (tablets, capsules) and topical gels/creams designed for enhanced drug delivery.
• Solubility-Enhanced NSAID Products: Development of fast-acting oral analgesics and anti-inflammatory medications with improved onset of action.
• Topical Pain Relief: Used in transdermal patches, gels, and creams for localized treatment of musculoskeletal pain, arthritis, and inflammation.
• Drug Delivery Research: A model compound in R&D for studying cyclodextrin complexation technologies and controlled release mechanisms.
• Veterinary Pharmaceuticals: Formulation of improved anti-inflammatory treatments for animal health.

Basic Information

Product Name	Piroxicambeta-Cyclodextrin
CAS No.	121696-62-6
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Piroxicam β-Cyclodextrin Complex; Piroxicam/β-Cyclodextrin Inclusion Complex; Piroxicam-β-CD; Piroxicam Betadex; Piroxicam Cyclodextrin Clathrate; 4-Hydroxy-2-methyl-N-(2-pyridyl)-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxide compound with β-Cyclodextrin
EINECS	Contact for details

Quality Control

Our Piroxicambeta-Cyclodextrin is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, complexation efficiency, and compliance with relevant pharmaceutical development guidelines. A comprehensive Certificate of Analysis (COA) documenting assay, related substances, residual solvents, and microbiological quality is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a low-humidity environment to prevent moisture uptake and maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Complexation Efficiency	Contact for details
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 10.0%
Residual Solvents (GC)	Complies with ICH Q3C
Microbiological Quality	Meets standard bioburden limits for non-sterile APIs

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.