Description

Piperazine-1,4-Dicarboxylic Acid Benzyl Ester tert-Butyl Ester is a key protected piperazine derivative used as a versatile building block in advanced organic synthesis. This compound is essential for researchers and manufacturers requiring high-purity intermediates for complex molecule construction. It is primarily utilized in the pharmaceutical industry for the development of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry and peptide synthesis.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of complex drug molecules, particularly those containing a piperazine core.
• Peptide Chemistry: Used in the preparation of protected amino acid derivatives and peptide mimetics for drug discovery.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and library synthesis.
• Agrochemical Synthesis: Potential intermediate in the development of novel crop protection agents and herbicides.
• Material Science: Can be employed in the synthesis of specialty polymers and functional materials.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs for bespoke chemical production.

Basic Information

Product Name	Piperazine-1,4-Dicarboxylic Acid Benzyl Ester tert-Butyl Ester
CAS No.	121370-60-3
Molecular Formula	C18H26N2O4
Molecular Weight	334.41 g/mol
Synonyms	1,4-Piperazinedicarboxylic acid, 1,4-bis(1,1-dimethylethyl) ester, 1,4-dibenzyl ester; 1,4-Di-tert-butyl 1,4-dibenzyl piperazine-1,4-dicarboxylate; tert-Butyl 1-benzyl 4-(benzyloxycarbonyl)piperazine-1,4-dicarboxylate; 1,4-Di-Boc-1,4-dibenzyl piperazine; N,N'-Di-Boc-N,N'-dibenzylpiperazine; Piperazine-1,4-dicarboxylic acid dibenzyl ester di-tert-butyl ester; 1,4-Bis(tert-butoxycarbonyl)-1,4-dibenzylpiperazine
EINECS	Contact for details

Quality Control

Our Piperazine-1,4-Dicarboxylic Acid Benzyl Ester tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our commitment to quality supports applications in GMP and non-GMP pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider storing under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.