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1,3-Dipalmitoyl-2-(4-Aminobutyryl)Glycerol CAS NO 121067-20-7


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CAS No.:121067-20-7

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

1,3-Dipalmitoyl-2-(4-Aminobutyryl)Glycerol is a synthetic, structured glycerolipid derivative that combines a glycerol backbone with palmitic acid and a 4-aminobutyryl moiety. This unique molecular architecture makes it a valuable intermediate for advanced research and development in lipid-based drug delivery systems and functional biomaterials. It is primarily sought by pharmaceutical researchers, formulation scientists, and specialty chemical manufacturers working on liposomal formulations, prodrug synthesis, and novel excipient development.

Application

  • Pharmaceutical Intermediate: A key building block for the synthesis of novel prodrugs and targeted lipid conjugates to enhance drug solubility and bioavailability.
  • Lipid Nanoparticle (LNP) Research: Used in the development and optimization of non-viral delivery vectors for mRNA, siRNA, and other nucleic acid therapeutics.
  • Liposome Formulation: Serves as a functional component to modify the surface charge, stability, and targeting properties of liposomal carriers.
  • Biomaterial Science: Employed in creating functionalized lipid membranes, coatings, and scaffolds for biomedical applications.
  • Bioconjugation Chemistry: The primary amine group provides a handle for covalent attachment to peptides, proteins, or other active molecules.
  • Reference Standard: Used as a high-purity analytical standard in quality control and method development for lipid analysis.

Basic Information

Product Name 1,3-Dipalmitoyl-2-(4-Aminobutyryl)Glycerol
CAS No. 121067-20-7
Molecular Formula C39H75NO6
Molecular Weight 654.02 g/mol
Synonyms 1,3-Dihexadecanoyl-2-(4-aminobutanoyl)-sn-glycerol; 2-(4-Aminobutyryl)-1,3-dipalmitoyl-glycerol; 4-Aminobutyric Acid 1,3-Dipalmitoyl Glycerol Ester; DPPG-ABG; Glycerol, 1,3-dipalmitoyl-2-(4-aminobutyryl)-; N/A
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Quality Control

Our 1,3-Dipalmitoyl-2-(4-Aminobutyryl)Glycerol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and residual solvent analysis, to ensure it meets the stringent requirements for research and development applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere for long-term stability. The product is hygroscopic (moisture-sensitive) and should be allowed to equilibrate to room temperature in a desiccator before opening to prevent condensation.

Specification

Item Specification
Appearance White to off-white solid
Identification (IR) Conforms to structure
Identification (NMR) Conforms to structure
Assay (HPLC) ≥ 95.0%
Water Content (KF) ≤ 1.0%
Residual Solvents (GC) Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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