Description

(-)-Mycalolide A CAS NO 121038-36-6 is a potent, naturally occurring macrolide compound originally isolated from marine sponges of the genus *Mycale*. This compound is of significant interest due to its powerful and specific actin-depolymerizing activity, which disrupts the cellular cytoskeleton. It serves as a critical research tool for cell biologists and pharmacologists investigating cytoskeletal dynamics, cell motility, and the development of novel therapeutic agents targeting these pathways.

Application

• Biochemical Research: Used as a highly specific actin filament destabilizing agent to study cytoskeleton organization, cell division, and morphology.
• Pharmacology & Drug Discovery: Serves as a lead compound or molecular probe for developing new anti-cancer and anti-metastatic drugs that target actin polymerization.
• Cell Biology Studies: Employed to investigate processes such as cell migration, adhesion, and intracellular transport that are dependent on actin dynamics.
• Mechanism of Action (MoA) Research: Utilized to elucidate biological pathways and validate molecular targets in various disease models.
• Marine Natural Product Chemistry: Acts as a reference standard for the isolation, identification, and synthesis of complex marine-derived bioactive molecules.

Basic Information

Product Name	(-)-Mycalolide A
CAS No.	121038-36-6
Molecular Formula	C47H70N2O11
Molecular Weight	839.1 g/mol
Synonyms	Mycalolide A; (-)-Mycalolide A; Mycalolide-A; (3S,4S,5S,7R,8S,9S,11S,12R,13S,14S,16R,18S,19S,20R,22S,23S,24S,26S,27S,29S,30S,32S,33S,34S,36S,37S,38S,40S,41S,42S,44S,45S,46S,48S,49S,50S,52S,53S,54S,56S,57S,58S,60S,61S,62S,64S,65S,66S,68S,69S,70S)-Form (IUPAC); Marine macrolide toxin; Actin polymerization inhibitor
EINECS	Contact for details

Quality Control

Our (-)-Mycalolide A is produced and handled under strict quality protocols suitable for research applications. Each batch undergoes comprehensive analytical testing, including HPLC for purity verification and structural confirmation via spectroscopic methods. A detailed Certificate of Analysis (COA) is provided, ensuring traceability and compliance with the specifications required for advanced life science research.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below. Allow the product to equilibrate to room temperature before opening to minimize moisture condensation. Keep the container in a dry environment.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Solubility	Soluble in DMSO, DMF; sparingly soluble in methanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.