Description

1-Piperidinepropanol, α-Cyclohexyl-4-(3-Hydroxyphenyl)-3,4-Dimethy L- is a complex organic compound featuring a piperidine-propanol backbone with cyclohexyl and hydroxyphenyl substituents, making it a versatile chiral building block. This compound matters for its role as a key synthetic intermediate in the development of advanced pharmaceutical actives and fine chemicals, where its specific stereochemistry is critical. It is primarily needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: Serves as a crucial chiral synthon in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and cardiovascular targets.
• Agrochemical Research: Used in the development of advanced herbicides, fungicides, and plant growth regulators where specific stereochemistry influences biological activity.
• Ligand and Catalyst Precursor: Acts as a starting material for the synthesis of chiral ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Fine Chemical Synthesis: Employed in custom synthesis and contract manufacturing for producing high-value, complex organic molecules.
• Material Science Research: Investigated as a monomer or additive for specialty polymers with tailored thermal or optical properties.
• Academic & Industrial R&D: Utilized in medicinal chemistry programs and process chemistry optimization for route scouting and scale-up studies.

Basic Information

Item	Detail
Product Name	1-Piperidinepropanol, α-Cyclohexyl-4-(3-Hydroxyphenyl)-3,4-Dimethy L-
CAS No.	120938-72-9
Molecular Formula	C22H35NO2
Molecular Weight	345.52 g/mol
Synonyms	α-Cyclohexyl-4-(3-hydroxyphenyl)-3,4-dimethyl-1-piperidinepropanol; 4-(3-Hydroxyphenyl)-3,4-dimethyl-α-cyclohexyl-1-piperidinepropanol; 1-Piperidinepropanol, α-cyclohexyl-4-(3-hydroxyphenyl)-3,4-dimethyl-; (α-Cyclohexyl-4-(3-hydroxyphenyl)-3,4-dimethyl-1-piperidinepropanol); UNII-7VQ27S6OQN; 7VQ27S6OQN; 1-Piperidinepropanol, α-cyclohexyl-4-(3-hydroxyphenyl)-3,4-dimethyl-, (αR)-; (R)-α-Cyclohexyl-4-(3-hydroxyphenyl)-3,4-dimethyl-1-piperidinepropanol
EINECS	Contact for details

Quality Control

Our 1-Piperidinepropanol, α-Cyclohexyl-4-(3-Hydroxyphenyl)-3,4-Dimethy L- is produced under a strict quality management system. Every batch undergoes rigorous analytical testing, including chiral purity assessment, to ensure consistent identity, purity, and composition. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing specifications and test results. Our quality commitment aligns with cGMP principles where applicable for pharmaceutical development, ensuring traceability and reliability for your critical R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound may be hygroscopic (moisture-sensitive); therefore, the container should be kept tightly sealed under an inert atmosphere if specified. Keep away from strong oxidizing agents, strong acids, and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (enantiomeric excess)
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Loss on Drying	≤ 0.5% w/w
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.