Description

5,12-Dihydroxy-6,8,14-Eicosatrienoic Acid is a specialized eicosanoid derivative, a class of bioactive lipid mediators with significant physiological relevance. This compound is valued for its role as a potential intermediate or reference standard in advanced biochemical and pharmacological research. It is primarily sought by professionals in the life sciences sector for applications in studying inflammatory pathways, lipid metabolism, and cellular signaling mechanisms.

Application

• Biochemical Research: Used as a critical reference standard or analytical standard in lipidomics and metabolomics studies.
• Pharmaceutical R&D: Serves as a key intermediate or building block in the synthesis of novel therapeutic agents targeting inflammation and immune response.
• Cell Signaling Studies: Employed in laboratory investigations to elucidate the role of hydroxy-eicosatrienoic acids in cellular communication and regulatory processes.
• Academic Research: Utilized in university and institutional labs for fundamental research on eicosanoid biology and related metabolic pathways.
• Diagnostic Development: Acts as a calibrant or component in the development of diagnostic assays for specific lipid biomarkers.

Basic Information

Product Name	5,12-Dihydroxy-6,8,14-Eicosatrienoic Acid
CAS No.	120904-46-3
Molecular Formula	C₂₀H₃₂O₄
Molecular Weight	336.47 g/mol
Synonyms	5,12-DiHETE; 5,12-Dihydroxy-6,8,14-eicosatrienoate; (6E,8Z,14Z)-5,12-Dihydroxyicosa-6,8,14-trienoic acid; 5,12-Dihydroxy-6,8,14-icosatrienoic acid; 5,12-DiHETrE; 5,12-Dihydroxy-6,8,14-ETrE; 5,12-Dihydroxy-6,8,14-eicosatrienoic acid (6E,8Z,14Z)-isomer
EINECS	Contact for details

Quality Control

Our 5,12-Dihydroxy-6,8,14-Eicosatrienoic Acid is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity, suitable for sensitive research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to rigorous analytical standards, utilizing techniques such as HPLC, NMR, and MS for verification, ensuring the material meets the exacting requirements of the scientific community.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to minimize oxidation and degradation. Allow the sealed container to reach room temperature before opening to prevent condensation and moisture ingress.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.