Description

1-Boc-2-Methylpiperazine is a high-purity, protected piperazine derivative of significant importance in advanced organic synthesis. This compound serves as a critical versatile building block for the construction of complex molecules, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides.
• Ligand and Catalyst Preparation: Serves as a precursor for creating chiral ligands and organocatalysts used in asymmetric synthesis.
• Peptidomimetics & Molecular Scaffolds: Employed in medicinal chemistry for constructing peptide analogs and diverse heterocyclic scaffolds in drug discovery programs.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for clients.
• Academic & Institutional Research: Used in university and institutional laboratories for methodological development and exploring new chemical reactions.

Basic Information

Product Name	1-Boc-2-Methylpiperazine
CAS No.	120737-78-2
Molecular Formula	C10H20N2O2
Molecular Weight	200.28 g/mol
Synonyms	tert-Butyl 2-methylpiperazine-1-carboxylate; 2-Methyl-1-piperazinecarboxylic acid 1,1-dimethylethyl ester; 1-(tert-Butoxycarbonyl)-2-methylpiperazine; N-Boc-2-methylpiperazine; Boc-2-methylpiperazine; 2-Methylpiperazine-1-carboxylic acid tert-butyl ester; 1-N-Boc-2-methylpiperazine
EINECS	Contact for details

Quality Control

Our 1-Boc-2-Methylpiperazine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specification results. Our quality commitment aligns with the standards expected for GMP-grade intermediates used in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.