Description

Bromfenac Sodium CAS NO 120638-55-3 is a potent nonsteroidal anti-inflammatory drug (NSAID) belonging to the phenylacetic acid derivative class. It is a critical active pharmaceutical ingredient (API) valued for its superior ocular penetration and anti-inflammatory efficacy. This compound is primarily required by pharmaceutical manufacturers and research institutions developing ophthalmic solutions for the treatment of postoperative inflammation and pain following cataract surgery.

Application

• Ophthalmic Formulations: Primary use as the active ingredient in prescription eye drops for treating inflammation and pain associated with cataract surgery.
• Pharmaceutical R&D: Serves as a key reference standard and intermediate in the research and development of novel NSAID-based therapeutics.
• Generic Drug Manufacturing: Essential for the production of generic versions of branded bromfenac ophthalmic solutions.
• Analytical Testing: Used as a high-purity standard in quality control (QC) and analytical laboratories for method development and validation.
• Preclinical Studies: Employed in pharmacological and toxicological studies to investigate anti-inflammatory mechanisms and efficacy.

Basic Information

Product Name	Bromfenac Sodium
CAS No.	120638-55-3
Molecular Formula	C15H11BrNNaO3
Molecular Weight	356.15 g/mol
Synonyms	Bromfenac Sodium Salt; 2-Amino-3-(4-bromobenzoyl)benzenacetic acid sodium salt; Bromfenac Na; Y-41554; Sodium Bromfenac; (+-)-Bromfenac Sodium; Bromfenac Sodium Sesquihydrate; ( )-Bromfenac Sodium
EINECS	Contact for details

Quality Control

Our Bromfenac Sodium is manufactured under strict quality management systems. It undergoes rigorous analytical testing to ensure it meets high-purity standards suitable for pharmaceutical applications, including identification, assay, and impurity profile analysis. A comprehensive Certificate of Analysis (COA) is provided with each batch, detailing specifications and test results.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a low-humidity environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 8.0% (for sesquihydrate)
Related Substances (HPLC)	Individual impurity: ≤ 0.5% Total impurities: ≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.