Description

2H-Pyrido[1,2-A]Pyrazine-3-Methanol,Octahydro-(6Ci) is a complex, saturated heterocyclic compound of significant interest in advanced organic synthesis. This specialized chemical serves as a crucial chiral building block or intermediate for the development of novel pharmacologically active molecules. It is primarily utilized by pharmaceutical R&D and fine chemical manufacturers engaged in creating new therapeutic agents, particularly within the domains of central nervous system (CNS) and anti-infective drug discovery.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the multi-step synthesis of potential drug candidates targeting complex biological pathways.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new active pharmaceutical ingredients (APIs).
• Asymmetric Synthesis: Employed as a scaffold or precursor for constructing enantiomerically pure compounds due to its fused bicyclic structure with multiple stereocenters.
• Chemical Biology Probes: Serves as a core structure for developing molecular probes to study enzyme function or receptor interactions.
• Fine Chemical Production: Used in the custom synthesis of high-value, low-volume specialty chemicals for advanced applications.

Basic Information

Product Name	2H-Pyrido[1,2-A]Pyrazine-3-Methanol,Octahydro-(6Ci)
CAS No.	120614-00-8
Molecular Formula	C9H16N2O
Molecular Weight	168.24 g/mol
Synonyms	Octahydro-2H-pyrido[1,2-a]pyrazine-3-methanol; 3-(Hydroxymethyl)octahydro-2H-pyrido[1,2-a]pyrazine; 2H-Pyrido[1,2-a]pyrazine-3-methanol, octahydro-; (3S,8aS)-3-(Hydroxymethyl)octahydro-2H-pyrido[1,2-a]pyrazine (enantiomer); (3R,8aR)-3-(Hydroxymethyl)octahydro-2H-pyrido[1,2-a]pyrazine (enantiomer); Bicyclic amino alcohol intermediate
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems. Every batch is characterized and tested using advanced analytical techniques including HPLC, GC, NMR, and chiral analysis to ensure identity, purity, and enantiomeric excess meet rigorous customer specifications. Comprehensive Certificates of Analysis (COA) with full analytical data are provided, and custom synthesis under cGMP guidelines can be discussed for pharmaceutical development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0% (Specific enantiomer available)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.