Description

1-(5-Trifluoromethyl-Pyridin-2-Yl)-Piperazine Dihydrochloride is a high-purity, advanced pharmaceutical intermediate characterized by its piperazine-pyridine hybrid structure. This compound is critical for research and development in medicinal chemistry, particularly in the synthesis of novel active pharmaceutical ingredients (APIs) targeting central nervous system and other therapeutic areas. It is primarily utilized by pharmaceutical manufacturers, biotechnology R&D laboratories, and fine chemical synthesis specialists seeking a reliable building block for complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those with potential neurological or psychiatric applications.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes in drug discovery pipelines.
• Active Pharmaceutical Ingredient (API) Synthesis: Serves as a precursor in multi-step synthetic routes for the production of target APIs.
• Biochemical Tool Compound: Employed in the development of research probes and ligands for studying biological targets and pathways.
• Fine Chemical Manufacturing: Utilized in custom synthesis and contract manufacturing of complex, high-value specialty chemicals.

Basic Information

Product Name	1-(5-Trifluoromethyl-Pyridin-2-Yl)-Piperazine Dihydrochloride
CAS No.	120298-11-5
Molecular Formula	C10H13Cl2F3N3
Molecular Weight	294.13 g/mol
Synonyms	1-[5-(Trifluoromethyl)pyridin-2-yl]piperazine dihydrochloride; 2-(1-Piperazinyl)-5-(trifluoromethyl)pyridine dihydrochloride; 5-Trifluoromethyl-2-piperazin-1-ylpyridine dihydrochloride; 1-(5-Trifluoromethyl-2-pyridinyl)piperazine dihydrochloride; 1-(5-Trifluoromethylpyridin-2-yl)piperazine hydrochloride (1:2); 120298-11-5; TFP Dihydrochloride
EINECS	Contact for details

Quality Control

Our 1-(5-Trifluoromethyl-Pyridin-2-Yl)-Piperazine Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals, to ensure it meets the stringent requirements for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.