Description

Insulin, (Arg-Insulin) CAS NO 120022-04-0 is a high-purity, synthetic insulin analog where an arginine residue has been incorporated into the peptide sequence. This modification is of significant interest in pharmaceutical research and development for creating novel therapeutic agents with potentially enhanced stability or altered pharmacokinetic profiles. It is primarily utilized by biotechnology firms, pharmaceutical R&D laboratories, and academic research institutions focused on endocrinology, diabetes treatment, and peptide-based drug discovery.

Application

• Pharmaceutical Research & Development: As a key intermediate or reference standard in the development of next-generation insulin therapies and biosimilars.
• Biochemical Studies: For investigating insulin receptor binding affinity, signal transduction pathways, and the structure-activity relationship (SAR) of modified insulin peptides.
• Reference Standard: Serves as a high-purity analytical standard for quality control and assay validation in insulin manufacturing processes.
• Preclinical Studies: Used in animal models to study the efficacy, metabolism, and safety profiles of arginine-modified insulin analogs.
• Peptide Chemistry: Valuable building block for further chemical conjugation or formulation studies in advanced drug delivery systems.

Basic Information

Product Name	Insulin, (Arg-Insulin)
CAS No.	120022-04-0
Molecular Formula	C257H383N65O77S6
Molecular Weight	5807.9 g/mol (approx.)
Synonyms	Arg-Insulin; Arginine-Insulin; Insulin Arginine Analog; Insulin (Arg-modified); Recombinant Arg-Insulin; Insulin analog with arginine substitution; Therapeutic Insulin Analog; CAS 120022-04-0
EINECS	Contact for details

Quality Control

Our Insulin, (Arg-Insulin) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and biological activity, meeting the stringent requirements for research-grade biopharmaceuticals. Certificates of Analysis (COA) detailing purity (by HPLC), peptide content, endotoxin levels, and bioactivity are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store frozen at -20°C or below for long-term stability. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature before opening to prevent condensation. For short-term use, aliquots may be stored at 2-8°C for up to one week.

Specification

Item	Specification
Appearance	White or off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Peptide Content	≥ 80.0%
Water Content (KF)	≤ 5.0%
Biological Activity	Assessed by in vitro assay
Endotoxin	< 10 EU/mg

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.