Description

Glucagon-Like Peptide I (7-36)Amide is a bioactive peptide fragment of the incretin hormone GLP-1, known for its role in glucose metabolism. This compound is a critical research tool and a key intermediate in the development of therapeutic agents for metabolic disorders. It is primarily utilized by pharmaceutical R&D teams, academic researchers, and biotech companies focused on endocrinology and diabetes research.

Application

• Pharmaceutical Research & Development: As a reference standard and active pharmaceutical ingredient (API) intermediate in the development of novel GLP-1 receptor agonists for Type 2 Diabetes and obesity treatments.
• Biochemical Research: Used in in vitro and in vivo studies to investigate the mechanisms of insulin secretion, β-cell function, and appetite regulation.
• Analytical Standard: Serves as a high-purity calibrant in HPLC, LC-MS, and other analytical methods for quality control and method validation in peptide synthesis.
• Peptide Synthesis: A key building block for the chemical synthesis of longer GLP-1 analogs and conjugate molecules in medicinal chemistry.

Basic Information

Product Name	Glucagon-Like Peptide I (7-36)Amide
CAS No.	119637-73-9
Molecular Formula	C₁₄₉H₂₂₆N₄₀O₄₈
Molecular Weight	3297.6 g/mol
Synonyms	GLP-1 (7-36) amide; Glucagon-like peptide 1 (7-36)-amide; Incretin hormone fragment; GLP-I (7-36)NH2; H-His-Asp-Glu-Phe-Glu-Arg-His-Ala-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys-Glu-Phe-Ile-Ala-Trp-Leu-Val-Lys-Gly-Arg-NH2; GLP-1 amide; Tirzepatide intermediate
EINECS	Contact for details

Quality Control

Our Glucagon-Like Peptide I (7-36)Amide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, MS for identity confirmation, and tests for residual solvents and endotoxins. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with research-grade standards. Specifications can be aligned with cGMP guidelines for advanced preclinical and clinical development stages.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dedicated freezer. This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccant and under an inert atmosphere. Allow the vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Peptide Content	≥ 80.0%
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%
Endotoxins	< 10 EU/mg

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.