Description

2-Methyl-8-Quinoxalinesulfonyl Chloride is a specialized sulfonyl chloride derivative of the quinoxaline heterocycle, serving as a critical building block in advanced organic synthesis. Its primary value lies in its high reactivity as a sulfonylation reagent, enabling the efficient introduction of the unique 2-methylquinoxaline-8-sulfonyl moiety into target molecules. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and functional materials where precise molecular modification is required.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, especially protease inhibitors and kinase-targeted therapeutics.
• Agrochemical Synthesis: Used in creating novel herbicides, fungicides, and insecticides with the quinoxaline scaffold.
• Material Science Research: Building block for developing advanced polymers, liquid crystals, and organic electronic materials.
• Bioconjugation & Probe Development: Reactive handle for labeling biomolecules (proteins, peptides) in biochemical research and diagnostic assay development.
• Chemical Library Synthesis: Valuable reagent for medicinal chemistry programs aiming to generate diverse compound libraries for high-throughput screening.
• Dye & Pigment Intermediate: Used in the synthesis of specialized heterocyclic dyes and colorants.

Basic Information

Product Name	2-Methyl-8-Quinoxalinesulfonyl Chloride
CAS No.	119373-30-7
Molecular Formula	C9H7ClN2O2S
Molecular Weight	242.68 g/mol
Synonyms	8-Quinoxalinesulfonyl chloride, 2-methyl-; 2-Methylquinoxaline-8-sulfonyl chloride; 2-Methyl-8-quinolinesulfonyl chloride (common misnomer); 2-Methyl-8-sulfonylchloride quinoxaline; 119373-30-7; 2-Methylquinoxalin-8-ylsulfonyl chloride
EINECS	Contact for details

Quality Control

Our 2-Methyl-8-Quinoxalinesulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and process chemistry. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting batch-specific results.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases, alcohols, and amines.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.