Description

Glidobactin G is a potent, naturally occurring cyclic depsipeptide antibiotic belonging to the glidobactin family. This compound is of significant interest in pharmaceutical research and development due to its unique mechanism of action and potent biological activity against a range of targets. It is primarily utilized by researchers in the life sciences, biotechnology, and pharmaceutical industries for advanced drug discovery programs, mechanism of action studies, and as a critical reference standard. Its high purity and structural integrity are essential for ensuring reliable and reproducible experimental results.

Application

• Pharmaceutical Research & Drug Discovery: Serves as a key reference compound and a lead structure for developing novel anti-infective and anti-cancer therapeutics.
• Mechanism of Action Studies: Used in biochemical and microbiological assays to investigate proteasome inhibition and other specific cellular pathways.
• Biological Standard: Acts as a certified reference material (CRM) for analytical method development, validation, and quality control in laboratory settings.
• Academic Research: Employed in university and institutional labs for studying natural product biosynthesis, structure-activity relationships (SAR), and microbial resistance.
• Biotechnology Applications: Potential use in cell biology research to probe protein degradation processes and cellular homeostasis.

Basic Information

Product Name	Glidobactin G
CAS No.	119259-71-1
Molecular Formula	C36H59N7O9
Molecular Weight	733.90 g/mol
Synonyms	Glidobactin G; CPD 0; Antibiotic CPD 0; Cyclo[(2S,3S)-3-hydroxy-2-methylpentanoyl-L-leucyl-D-seryl-(3S,4E)-3-hydroxy-7-methyl-4-octenoyl-L-arginyl-L-glutaminyl]; (3S,6S,9S,15S,18S,32S)-6,9,18-Tris(1-hydroxyethyl)-3,15,32-trimethyl-1,4,7,10,13,16,19,22,25,28,31-undecaazacyclotetratriacontane-2,5,8,11,14,17,20,23,26,29,33-undecone
EINECS	Contact for details

Quality Control

Every batch of Glidobactin G is manufactured and analyzed under strict quality management systems. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure identity, purity, and potency compliance with research-grade standards. A comprehensive Certificate of Analysis (COA) detailing batch-specific results is provided with each shipment to guarantee traceability and support your regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dedicated freezer. The product is hygroscopic (moisture-sensitive); ensure the container is sealed under an inert atmosphere after each use to maintain long-term stability. Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines
Biological Activity	Assay-dependent; COA provided

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.