Description

Dextran Naproxen Ester is a specialized pharmaceutical conjugate designed for targeted drug delivery and controlled release applications. This compound is engineered to enhance the therapeutic profile of the non-steroidal anti-inflammatory drug (NSAID) naproxen by covalently linking it to a biocompatible dextran polymer backbone. It is primarily utilized by advanced pharmaceutical researchers and manufacturers developing novel parenteral formulations and sustained-release drug delivery systems. The product is supplied under the identifier CAS NO 119166-66-4.

Application

• Development of sustained-release injectable formulations for prolonged anti-inflammatory and analgesic effects.
• Research into targeted drug delivery systems, particularly for site-specific inflammation treatment.
• As a key intermediate in the synthesis of advanced polymer-drug conjugates for improved pharmacokinetics.
• Preclinical and clinical studies for novel parenteral NSAID delivery platforms.
• Formulation of biodegradable implant materials for localized, long-term pain management.
• Investigation of macromolecular prodrugs to reduce gastrointestinal side effects associated with traditional NSAIDs.

Basic Information

Product Name	Dextran Naproxen Ester
CAS No.	119166-66-4
Molecular Formula	Contact for details
Molecular Weight	Variable (Polymer conjugate)
Synonyms	Naproxen-Dextran Conjugate; Dextran-(2-(6-methoxynaphthalen-2-yl)propanoate); Dextran-Naproxen Prodrug; Naproxen Dextran Ester; Polymeric Naproxen Prodrug; Dextran Linked Naproxen; Naproxen Macromolecular Conjugate; S-NAP-DEX
EINECS	Contact for details

Quality Control

Our Dextran Naproxen Ester is manufactured under strict quality systems suitable for pharmaceutical research and development. Each batch undergoes rigorous analytical testing to ensure consistent polymer-drug ratio, purity, and molecular weight distribution. Certificates of Analysis (COA) detailing key parameters such as drug loading content, free naproxen content, and residual solvents are provided with every shipment to support your regulatory and research needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term stability, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Drug Loading (Naproxen Content)	Contact for details
Free Naproxen	< 2.0%
Moisture Content (KF)	< 5.0%
Molecular Weight (Average)	Specified per grade (e.g., 10kDa, 40kDa, 70kDa)
Solubility	Soluble in DMSO, partially soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.