Description

Piperazine, 1-(3,5-Dimethoxybenzoyl)-, Monohydrochloride is a high-purity, functionalized piperazine derivative designed for advanced chemical synthesis. This compound serves as a critical pharmacologically active intermediate and a versatile building block for creating complex molecular architectures. It is primarily utilized by pharmaceutical R&D and fine chemical synthesis teams requiring precise and reliable raw materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and other therapeutic areas.
• Chemical Synthesis Building Block: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization due to its functionalized piperazine core.
• Research & Development: Essential for academic and industrial research laboratories exploring new heterocyclic compounds and their biological activities.
• Custom Synthesis: Serves as a starting material for contract research and manufacturing organizations (CROs/CMOs) producing specialized fine chemicals.
• Process Chemistry: Employed in the scale-up and optimization of synthetic routes for drug candidates during development phases.

Basic Information

Product Name	Piperazine, 1-(3,5-Dimethoxybenzoyl)-, Monohydrochloride
CAS No.	119049-62-6
Molecular Formula	C13H19ClN2O3
Molecular Weight	286.76 g/mol
Synonyms	1-(3,5-Dimethoxybenzoyl)piperazine hydrochloride; 3,5-Dimethoxy-N-(piperazin-1-yl)benzamide hydrochloride; N-(Piperazin-1-yl)-3,5-dimethoxybenzamide monohydrochloride; 3,5-Dimethoxybenzoylpiperazine HCl; 1-(3,5-Dimethoxybenzoyl)piperazine HCl; 119049-62-6; (3,5-Dimethoxyphenyl)(piperazin-1-yl)methanone hydrochloride
EINECS	Contact for details

Quality Control

Our Piperazine, 1-(3,5-Dimethoxybenzoyl)-, Monohydrochloride is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting full specifications are available for every shipment, supporting compliance in regulated environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.